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Chemical Structure| 135410-04-7 Chemical Structure| 135410-04-7

Structure of 135410-04-7

Chemical Structure| 135410-04-7

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Product Details of [ 135410-04-7 ]

CAS No. :135410-04-7
Formula : C9H13Cl2N3
M.W : 234.13
SMILES Code : CC(N(CC1=CC=C(Cl)N=C1)C)=N.[H]Cl

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Application In Synthesis of [ 135410-04-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 135410-04-7 ]

[ 135410-04-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 135410-04-7 ]
  • [ 6914-79-0 ]
  • C16H17ClN4O [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; at 0 - 25℃; for 15h; General procedure: 2. Preparation of N-[1 -[(6-chloropyridyl-3-yl)methyl]-methylamino]ethyliden acylam ides To a solution of the acid (10 mmol) of the formula (2), N-[(6-chloro-3-pyridyl)methyl]-N- methyl-acetamidine (11 mmol) of the formula (1), and PyBrop (12.50 mmol) in OH2Ol2 (20 mL) at 0 00 DIEA (40 mmol) was added in a dropwise manner. The reaction mixture was then allowed to stir at room temperature for 15 hours. The reaction mixture was then diluted with saturated aqueous Na HOC3, phases are separated, and the organic phase is extracted twicewith 0H2012, dried over Na2S04, filtered and concentrated in vacuo. The product of the formula (l-A.la)was then isolated via column chromatography.
 

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