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Chemical Structure| 1356054-74-4 Chemical Structure| 1356054-74-4

Structure of 1356054-74-4

Chemical Structure| 1356054-74-4

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Product Details of [ 1356054-74-4 ]

CAS No. :1356054-74-4
Formula : C7H8IN3
M.W : 261.06
SMILES Code : IC1=CN=CN=C1N2CCC2

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Application In Synthesis of [ 1356054-74-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1356054-74-4 ]

[ 1356054-74-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 503-29-7 ]
  • [ 63558-65-6 ]
  • [ 1356054-74-4 ]
YieldReaction ConditionsOperation in experiment
92% With caesium carbonate; In 1,2-dimethoxyethane; at 90℃; for 18h;Inert atmosphere; capped; To a 16x100 mm reaction tube under 2 was added <strong>[63558-65-6]4-chloro-5-iodopyrimidine</strong> (200 mg, 0.832 mmol), cesium carbonate (817 mg, 2.508 mmol) and 1,2- dimethoxyethane (5 mL). The reaction mixture was flushed with nitrogen and then treated with azetidine (1 12 mu^, 1.662 mmol). The reaction mixture was securely capped, stirred at room temperature for 5 min, and then heated at 90C for 18h. The reaction mixture was filtered through a small Celite plug by gravity, washed with dichloromethane (70 mL) and the solvent was evaporated off in vacuo to give 200 mg (92%) of the title compound as a pale yellow solid.
 

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