Home Cart Sign in  
Chemical Structure| 1359711-06-0 Chemical Structure| 1359711-06-0

Structure of 1359711-06-0

Chemical Structure| 1359711-06-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1359711-06-0 ]

CAS No. :1359711-06-0
Formula : C15H17NO4
M.W : 275.30
SMILES Code : O=C(N1CCCC=C1C(OC)=O)OCC2=CC=CC=C2
MDL No. :MFCD22689978

Safety of [ 1359711-06-0 ]

Application In Synthesis of [ 1359711-06-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1359711-06-0 ]

[ 1359711-06-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 180609-56-7 ]
  • [ 1359711-06-0 ]
YieldReaction ConditionsOperation in experiment
68% To a solution of Cbz-Pip-OMe (832 mg, 3 mmol) in dry THF (15 ml) at -78 C, a solution 1 M of LiHMDS in THF (4.5 ml, 4.5 mmol) was added and the mixture was stirred for 30 min. Then, the lithium enolate was added to a solution of PhSeCl (1.15 g, 6.0 mmol) in dry THF (15 ml) at -78 C. The reaction mixture was stirred for 24 h and reach slowly room temperature. The solvent was evaporated and the crude of the reaction was purify by flash chromatography using as eluent a mixture of ethyl acetate/hexane (3:7), affording 4 (562 mg, 2.04 mmol, 68 %). 1H NMR (CDCl3) delta 7.38-7.29 (m, 5H, Ar), 6.07 (t, J = 4.0 Hz, 1H, C=CH), 5.14 (s, 2H, CCbzH2), 3.67-3.64 (m, 2H, H), 3.55 (s, 3H, OCH3), 2.24 (dt, J = 6.6 and 3.9 Hz, 2H, H) and 1.86-1.80 (m, 2H, H) ppm; 13C NMR (CDCl3) delta 165.1 (COOMe), 135.8 (C), 132.4 (C, Ar), 128.5, 128.2 and 128.1 (CH, Ar), 123.1 (CH, C=C), 68.0 (CCbzH2), 51.9 (OCH3), 43.7 (Ce), 22.9 (Cg) and 22.7 (Cd) ppm; IR (neat) nu 1703, 1645, 1498, 1454, 1436 cm-1; HRMS (m/z): Calcd. for C15H17NO4[M+Na]+ 298.1049; Found 298.1059.
 

Historical Records