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Chemical Structure| 1369513-95-0 Chemical Structure| 1369513-95-0

Structure of 1369513-95-0

Chemical Structure| 1369513-95-0

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Product Details of [ 1369513-95-0 ]

CAS No. :1369513-95-0
Formula : C14H12ClN5O
M.W : 301.73
SMILES Code : ClC1=CC=C(C2(C3=NOC(C4=CNN=C4)=N3)CCC2)C=N1
MDL No. :MFCD28133650

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1369513-95-0 ]

[ 1369513-95-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 37718-11-9 ]
  • [ 1369513-85-8 ]
  • [ 1369513-95-0 ]
YieldReaction ConditionsOperation in experiment
Synthesis of 2-Chloro-5-{l-r5-(lH-pyrazol-4-yl)-l,2,4-oxadiazol-3-yll-cvclobutyl}- pyridine (Intermediate 1-4.2)1-2.1 R1 1 R12 |_4 2 Rl l (156 mg, 1.40 mmol) is treated with pyridine (10.0 mL) and R12 (116 mu,, 1.60 mmol) and the resulting mixture is stirred for 30 minutes. 1-2.1 (300 mg, 1.33 mmol) is then added and the reaction is stirred at 110 °C for 18 hours. The resulting mixture is cooled to room temperature and the solvent is removed in vacuo. The residue is partitioned between CH2C12 and saturated aqueous NaHC03 and the phases are separated. The organic phase is dried over Na2S04, filtered, and the solvent is removed in vacuo to give 1-4.2 (187 mg); m/z 301.9 [M+H].
 

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