Home Cart Sign in  
Chemical Structure| 1370448-67-1 Chemical Structure| 1370448-67-1

Structure of 1370448-67-1

Chemical Structure| 1370448-67-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1370448-67-1 ]

CAS No. :1370448-67-1
Formula : C8H8BrNO3
M.W : 246.06
SMILES Code : O=C(O)C1=CN=C(OCC)C(Br)=C1
MDL No. :MFCD29993766

Safety of [ 1370448-67-1 ]

Application In Synthesis of [ 1370448-67-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1370448-67-1 ]

[ 1370448-67-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 850568-54-6 ]
  • [ 1370448-67-1 ]
  • [ 1370448-66-0 ]
YieldReaction ConditionsOperation in experiment
A slurry of 5- bromo-6-ethoxynicotinic acid (60 mg, 0.24 mmol), 4-tert- butoxycarbonylphenylboronic acid (70 mg, 0.32 mmol), 2 N aqueous sodium carbonate (0.37 mL, 0.73 mmol) and palladium 1 ,1 '-bis(diphenylphosphino)ferrocene dichloride (9 mg, 0.05 mmol) in p-dioxane (2 mL) were heated at 100°C for 2 hr. An additional portion of 4-tert-butylcarboxylphenylboronic acid (70 mg, 0.32 mmol) and palladium 1 ,1 '-bis(diphenylphosphino)ferrocene dichloride (9 mg, 0.05 mmol) were added and heating was continued for 1 .5 hr. The reaction mixture was cooled, diluted into water, pH adjusted to ~5 using 1 N aqueous hydrochloric acid. This mixture was extracted with ethyl acetate (3x), the combined organic layers washed with brine, dried over magnesium sulfate and concentrated in vacuo to afford the title compound (100 mg), which was utilized without further purification; m/z = 344.2 (M+1 ).
 

Historical Records