Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 137046-58-3 | MDL No. : | |
Formula : | C10H8BrNO2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | - |
M.W : | 254.08 | Pubchem ID : | - |
Synonyms : |
|
Signal Word: | Class: | ||
Precautionary Statements: | UN#: | ||
Hazard Statements: | Packing Group: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
47% | With potassium <i>tert</i>-butylate In ethanol for 5h; Heating; Yields of byproduct given; | |
47% | With potassium <i>tert</i>-butylate In ethanol for 5h; Heating; Yield given. Title compound not separated from byproducts; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With sodium acetate; In acetic acid; | Example 21 This example describes the synthesis of 2-bromo-9-nitro-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one. 7-bromo-1H-[1]benzazepine-2,5(3H,4H)-dione (254 mg, 1 mmol), 4-nitro-phenylhydrazin hydrochloride (284 mg, 1.5 mmol), and sodium acetate (123 mg, 1.5 mmol) were stirred in glacial acetic acid (10 mL) for 1 hour at 70 C. After cooling to room temperature, the mixture was poured into 5% aqueous sodium acetate solution (20 mL). The precipitate was filtered off with suction, washed with water, and crystallized from ethanol to furnish 52% yellow crystals of precursor, 7-bromo-5-(4-nitro-phenylhydrazono)-4, 5-dihydro-]H-[1]benzazepin-2(3H)-one, mp. 300 C. (dec.); ir (KBr): 3220 (NH), 1670 (C=O); 1H-nmr (DMSO-d6, 400 MHz): delta (ppm) 2.56-2.59 and 3.02-3.06 (m, AA'XX', 4H, CH2-CH2), 6.99 (d, 1H, 8.1 Hz), 7.33 (d, 2H, 9.2 Hz), 7.56 (dd, 1H, 8.7/2.6 Hz), 7.75 (d, 1H, 2.0 Hz), 8.16 (d, 2H, 9.6 Hz), 9.87 (s, 1H, NH), 10.19 (s, 1H, NH); 13C-nmr(DMSO-d6, 100.6MHz): 6(ppm)=29.7,30.5, 112.4,116.2, 124.0, 125.8, 131.6, 132.1, 132.3, 136.8, 139.1, 147.1, 150.8, 172.7; C16H13BrN4O3 (389.22); Calcd. C 49.4, H 3.4, N 14.4, Br 20.5; Found C 49.1, H 3.4, N 14.1, Br 20.2. |