[ CAS No. 1370467-88-1 ]

Name: 1370467-88-1|7-Bromo-3-oxoisoindoline-4-carbonitrile|98%
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Quality Control of [ 1370467-88-1 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 1370467-88-1 ]

Product Details of [ 1370467-88-1 ]

CAS No. :	1370467-88-1	MDL No. :	MFCD27964212
Formula :	C₉H₅BrN₂O	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	MESWGGOFRUNGLK-UHFFFAOYSA-N
M.W :	237.05	Pubchem ID :	118486152
Synonyms :

Safety of [ 1370467-88-1 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362	UN#:
Hazard Statements:	H315-H319	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1370467-88-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 1370467-88-1 ]

[ 1370467-88-1 ] Synthesis Path-Downstream 1~23

1
[ 1370467-88-1 ]
[ 1616428-33-1 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran / 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

2
[ 1370467-88-1 ]
[ 1616428-34-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran / 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

3
[ 1370467-88-1 ]
[ 1616428-35-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: phosphorus pentachloride / diethyl ether / 0.67 h 4.2: 1 h / 0 - 20 °C 4.3: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

4
[ 1370467-88-1 ]
[ 1616428-36-4 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

5
[ 1370467-88-1 ]
[ CAS Unavailable ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: pyridine / N,N-dimethyl-formamide; tetrahydrofuran / 4 h 4.2: 0.33 h / 150 °C / Microwave irradiation

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

6
[ 1370467-88-1 ]
[ 1370467-92-7 ]

Yield	Reaction Conditions	Operation in experiment
66%	With pyridine; sodium dihydrogen phosphate monohydrate; acetic acid In water at 10 - 50℃; for 2h;	1.1 Synthesis of Compound B [0054] Compound A (40 g, 168 mmol) was dispersed in acetic acid (400 mL), added with water (400 mL) and pyridine(800 mL), and then the temperature of the mixture thus formed was lowered to 10°C. The mixture was added with sodiumphosphate monobasic monohydrate (280 g, 2.01 mol), and then further added with Raney Ni (101 g) in water (70 mL)to form a reaction solution. The reaction solution was heated to 50°C, allowed to react for 2 hours. Upon the completionof the reaction, the solution was cooled and filtered. The solution was washed with ethyl acetate (EA, 2.5 L), and thefiltrate was added with water (800 mL) for extraction. An organic layer thus formed was separated, and concentratedunder reduced pressure. Cooled water (800 mL) was added thereto, and a solid thus obtained was filtered and dried toobtain Compound B (26.7 g, yield: 66%).[0055] 1H-NMR Spectrum(300 MHz, DMSO-d6): 11.10(s, 1H), 9.15 (s, 1H), 7.95(d, J=8.1Hz, 1H), 7.78 (d, J=8.1Hz,1H), 4.41(s, 2H)[0056] LCMS [M+1]: 241.1

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1 Location in patent: Paragraph 0052; 0054; 0055; 0056

7
[ 1370467-88-1 ]
[ 1370467-93-8 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

8
[ 1370467-88-1 ]
[ 1370467-94-9 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

9
[ 1370467-88-1 ]
[ 1616428-18-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: pyridine / N,N-dimethyl-formamide; tetrahydrofuran / 4 h 4.2: 3 h / 20 °C 4.3: 0.5 h

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

10
[ 1370467-88-1 ]
[ 1616428-19-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran / 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

11
[ 1370467-88-1 ]
[ 1616428-20-6 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: phosphorus pentachloride / diethyl ether / 1 h 4.2: 2 h / 0 - 20 °C 4.3: 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

12
[ 1370467-88-1 ]
[ 1616428-21-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran / 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

13
[ 1370467-88-1 ]
[ 1616428-22-8 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: phosphorus pentachloride / diethyl ether / 1 h 4.2: 2 h / 0 - 20 °C 4.3: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

14
[ 1370467-88-1 ]
[ 1616428-23-9 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: tetrahydrofuran / 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

15
[ 1370467-88-1 ]
[ 1616428-24-0 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: pyridine / N,N-dimethyl-formamide; tetrahydrofuran / 4 h 4.2: 12 h / 100 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

16
[ 1370467-88-1 ]
[ 1616428-25-1 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: phosphorus pentachloride / diethyl ether / 0.67 h 4.2: 1 h / 0 - 20 °C 4.3: 3 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

17
[ 1370467-88-1 ]
[ 1616428-26-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: sodium hydrogencarbonate / methanol / 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

18
[ 1370467-88-1 ]
[ 1616428-27-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: triethylamine; diphenyl phosphoryl azide / tetrahydrofuran / 2 h / 20 °C 4.2: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

19
[ 1370467-88-1 ]
[ 1616428-28-4 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: phosphorus pentachloride / diethyl ether / 0.67 h 4.2: 1 h / 0 - 20 °C 4.3: 6 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

20
[ 1370467-88-1 ]
[ 1616428-29-5 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2.1: ammonia / water; ethanol / 3 h / 90 °C 3.1: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4.1: triethylamine; diphenyl phosphoryl azide / tetrahydrofuran / 1 h / 20 °C 4.2: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

21
[ 1370467-88-1 ]
[ 1616428-30-8 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

22
[ 1370467-88-1 ]
[ 1616428-31-9 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

23
[ 1370467-88-1 ]
[ 1616428-32-0 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: acetic acid; sodium dihydrogen phosphate monohydrate; pyridine / water / 2 h / 10 - 50 °C 2: ammonia / water; ethanol / 3 h / 90 °C 3: lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; ethanol; toluene; acetone; acetonitrile / 14 h / 80 - 85 °C 4: 4 h / 90 °C

Reference： [1]Current Patent Assignee: CRYSTAL GENOMICS INC - EP2940014, 2015, A1

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Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
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Prevention
Code	Phrase
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P220	Keep/Store away from clothing/combustible materials.
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P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
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P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
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P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
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P272	Contaminated work clothing should not be allowed out of the workplace.
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P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
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Response
Code	Phrase
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P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
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P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
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P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
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P321
P322
P330	Rinse mouth.
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P337	If eye irritation persists:
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P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
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P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
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P378
P380	Evacuate area.
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P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
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P401
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P411 + P235	Keep cool.
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Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1370467-88-1 ]

Quality Control of [ 1370467-88-1 ]

Related Doc. of [ 1370467-88-1 ]

Product Details of [ 1370467-88-1 ]

Safety of [ 1370467-88-1 ]

Application In Synthesis of [ 1370467-88-1 ]

[ 1370467-88-1 ] Synthesis Path-Downstream 1~23

Related Functional Groups of [ 1370467-88-1 ]

Bromides

Related Parent Nucleus of [ 1370467-88-1 ]

Indolines

Precautionary Statements-General

Prevention

Response

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Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1370467-88-1 ]

Related Parent Nucleus of
[ 1370467-88-1 ]