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Chemical Structure| 1382903-07-2 Chemical Structure| 1382903-07-2

Structure of 1382903-07-2

Chemical Structure| 1382903-07-2

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Product Details of [ 1382903-07-2 ]

CAS No. :1382903-07-2
Formula : C7H5Cl2IO2
M.W : 318.92
SMILES Code : ClC1=C(O)C(I)=C(OC)C(Cl)=C1

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Application In Synthesis of [ 1382903-07-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1382903-07-2 ]

[ 1382903-07-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1382903-07-2 ]
  • [ 22795-99-9 ]
  • [ 13939-06-5 ]
  • [ 84225-95-6 ]
YieldReaction ConditionsOperation in experiment
64% In a glovebox under argon, to chamber 1 of two- chamber system S2 was added Pd(dba)2 (19.9 mg, 0.0347 mmol), PPh3 (18.2 mg, 0.0693 mmol), 4,6-dichloro-2-iodo-3-methoxyphenol 37 (221 mg, 0.693 mmol), THF (3 ml_), (S)-(l-ethylpyrrolidin-2-yl)methanamine (193 muIota_, 1.39 mmol), TEA (194 muIota_, 1.39 mmol). The chamber was sealed with a screwcap fitted with a Teflon.(R). seal. In a glovebox under argon, to chamber 2 of two-chamber system S2 was added Mo(CO)6 (183 mg, 0.693 mmol), THF (3 ml_) and pyridine (280 muIota_, 3.47 mmol) in that order. The chamber was sealed with a screwcap fitted with a Teflon.(R). seal. The loaded two-chamber system was heated to 70 °C for 19 hours. The crude reaction mixture was evaporated on silica gel and the title compound 38 was obtained after flash chromatography (5percent MeOH in CH2CI2 as eluent) as brown oil (153.7 mg, 0.443 mmol, 64percent from 37).
  • 2
  • [ 1382903-07-2 ]
  • [ 22795-99-9 ]
  • [ 10456-04-9 ]
  • [11C-carbonyl]raclopride [ No CAS ]
 

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