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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 139755-70-7 Chemical Structure| 139755-70-7

Structure of 139755-70-7

Chemical Structure| 139755-70-7

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Product Details of [ 139755-70-7 ]

CAS No. :139755-70-7
Formula : C6H15NO3
M.W : 149.19
SMILES Code : OC(COCCCN)CO
MDL No. :MFCD10687000

Safety of [ 139755-70-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P260-P264-P280-P305+P351+P338-P405-P501
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 139755-70-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 139755-70-7 ]

[ 139755-70-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1426827-79-3 ]
  • [ 139755-70-7 ]
  • C17H27NO5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; at 20℃; General procedure: (R,S)-3-(3-aminopropoxy)propane-1 ,2-diol (1.64 g, 1 1 mmol) (Prepared according to the method of Misiura and Gait, WO 91 17169 A1 ) and VIIa (2.91 g, 10 mmol) are dissolved in anhydrous tetrahydrofuran (50 ml_) and stirred overnight at roomtemperature. The reaction solution is concentrated at reduced pressure and the residue is partitioned between ethyl acetate (50 ml.) and 5% aqueous Na2C03 (20 ml_). The organic layer is dried over Na2S04, filtered, and concentrated at reduced pressure. The residue is dissolved in anhydrous pyridine (30 ml_) and treated with dimethoxytrityl chloride (3.0 g, 9.0 mmol) and the resulting solution is stirred overnight at room temperature. The reaction is concentrated at reduced pressure and the resulting residue is partitioned between ethyl acetate and saturated aqueous NaHC03. The organic layer is washed with saturated aqueous NaCI, dried over Na2S04, filtered, and concentrated at reduced pressure. Flash chromatography on silica gel, eluting with a gradient of 5% to 45% ethyl acetate in hexanes affords 6a as a sticky foam upon evaporation of solvents at reduced pressure. MS (AP+): 628, (M+H).
 

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