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Chemical Structure| 1399327-71-9 Chemical Structure| 1399327-71-9

Structure of 1399327-71-9

Chemical Structure| 1399327-71-9

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Product Details of [ 1399327-71-9 ]

CAS No. :1399327-71-9
Formula : C14H9FN2
M.W : 224.23
SMILES Code : FC1=CC2=CN=C(C3=CC=CC=C3)N=C2C=C1
MDL No. :MFCD27922420

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Application In Synthesis of [ 1399327-71-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1399327-71-9 ]

[ 1399327-71-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 747392-34-3 ]
  • [ 1670-14-0 ]
  • [ 1399327-71-9 ]
YieldReaction ConditionsOperation in experiment
58% With potassium phosphate; copper(l) iodide; Trimethylacetic acid; In 1,2-dichloro-benzene; at 110℃; for 18h;Sealed tube; General procedure: Anoven-dried 10mLvialwas charged with CuI (9mg, 0.05mmol),K3PO4 (318 mg, 1.5 mmol), pivalic acid (20 mg, 0.2 mmol), a 1-(2-bromophenyl)methanamine 1 (0.5 mmol), and an amidinium salt 2or an imidate salt 4 (0.5 mmol) under air. After sealing the vial, dry1,2-dichlorobenzene (3 mL) was added by syringe and the reactionmixture was stirred at 110 C (oil bath temperature) for 18 h. Aftercooling to room temperature, the vial was opened and the reactionmixturewas partitioned between CH2Cl2 (30 mL) and brine (20 mL).The aqueous phase was extracted with CH2Cl2 (220 mL). Thecombined organic layers were dried over anhydrous MgSO4 andconcentrated in vacuum. The residue was purified by flash chromatographyon silica gel to afford the desired product.
 

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