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Chemical Structure| 1402609-40-8 Chemical Structure| 1402609-40-8

Structure of 1402609-40-8

Chemical Structure| 1402609-40-8

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Product Details of [ 1402609-40-8 ]

CAS No. :1402609-40-8
Formula : C7H11N3O
M.W : 153.18
SMILES Code : NC1=NN=C(OC)C(C)=C1C
MDL No. :MFCD22690214

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Application In Synthesis of [ 1402609-40-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1402609-40-8 ]

[ 1402609-40-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 124-41-4 ]
  • [ 76593-36-7 ]
  • [ 1402609-40-8 ]
YieldReaction ConditionsOperation in experiment
49% In methanol; at 30℃; for 1.0h;Microwave irradiation; 6-Chloro-4,5-dimethylpyridazin-3-amine (CAS-Nr. 76593-36-7, 500 mg,3.17 mmol, 1 .0 eq) in 14.51 ml_ of a 25% solution (w/w) of sodium methylate in MeOH was heated for 1 h at 130 C in a single mode microwave oven. The reaction mixture was partitioned between DCM and water. The organic phase was washed with brine and dried (Na2SO4 anh.). Volatile components were removed by the use of a rotary evaporator and the crude mixture was purified via MPLC (Biotage Isolera; 25 g SNAP NH2 cartridge: hexane-> hexane/EtOAc 1 /1 ) to give 250 mg (49% yield) of the title compound.1 H-NMR (400 MHz, d6-DMSO): δ [ppm] = 1 .98 (s, 3H), 2.00 (s, 3H), 5.49 (s, 3H), NH.2 not assigned.
 

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