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Chemical Structure| 1404562-18-0 Chemical Structure| 1404562-18-0

Structure of 1404562-18-0

Chemical Structure| 1404562-18-0

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Product Details of [ 1404562-18-0 ]

CAS No. :1404562-18-0
Formula : C11H9N3O2
M.W : 215.21
SMILES Code : NC1=CC(C2=CC=NC=C2)=CC=C1[N+]([O-])=O

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Application In Synthesis of [ 1404562-18-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1404562-18-0 ]

[ 1404562-18-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1404562-18-0 ]
  • [ 32315-10-9 ]
  • [ 6000-50-6 ]
  • C19H15N5O3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
39% To a solution of 102-1 (215 mg, 1.0 mmol), trimethylamine (TEA; 810 mg, 8.0 mmol) in dichloromethane (DCM; 10 mL) was added triphosgene (330 mg, 1.1 mmol) at ice bath. The mixture as warmed to room temperature and stirred for 3 h. TEA (202 mg, 2.0 mmol) and SM0 (230 mg, 1.2 mmol) was then added. The resulting solution was heated at 50 °C for 2 h. The mixture was cooled and diluted with DCM. The resultant was washed with brine, dried over Na2S04 and concentrated in vacuo. The residue was purified by column chromatography on silica gel (DCM : MeOH = 100 : 1 ~ 35 : 1) to give 102-2 (140 mg, 39 percent) as a yellow solid.
 

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