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Chemical Structure| 141-76-4 Chemical Structure| 141-76-4

Structure of 3-Iodopropionic Acid
CAS No.: 141-76-4

Chemical Structure| 141-76-4

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Product Citations

Product Citations

Morse, Jared ; Ofodum, Nnamdi ; Tang, Fung-Kit ; Schmidt, Matthias ; Lu, Xiaocun ; Leung, Kaho

Abstract: Chloride is the most abundant anion in cell physiology and plays many critical roles in maintaining cellular homeostasis. However, current chloride sensors are rare, with inherent sensitivity in their emission properties, such as vulnerability to pH changes or short emission lifetimes. These limitations restrict theirapplication in aqueous media and imaging. In this work, we employed a transition metal complex bearing pyridinium as a recognition unit for chloride and studied the phosphorescence emission properties. Iridium(III) complex 1 was synthesized as an alternative chloride-sensitive luminophore. The conjugable design also allows customization for desired applications. Complex 1 exhibited high sensitivity and selectivity in chloride sensing across different physiological environments, regardless of pH fluctuation and ionic strength. Additionally, complex 1 featured a long microsecond emission lifetime. The chloride sensing ability of complex 1 can be measured through both luminescence intensity and long-lived phosphorescent lifetime simultaneously, providing an alternative potential route for chloride imaging.

Keywords: Chloride ; chloride detection ; chloride-sensitive luminophore ; iridium complex

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Product Details of [ 141-76-4 ]

CAS No. :141-76-4
Formula : C3H5IO2
M.W : 199.98
SMILES Code : O=C(O)CCI
MDL No. :MFCD00002765
InChI Key :KMRNTNDWADEIIX-UHFFFAOYSA-N
Pubchem ID :8856

Safety of [ 141-76-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 141-76-4 ]

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