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Chemical Structure| 1415797-76-0 Chemical Structure| 1415797-76-0

Structure of 1415797-76-0

Chemical Structure| 1415797-76-0

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Product Details of [ 1415797-76-0 ]

CAS No. :1415797-76-0
Formula : C11H7ClFN3O3
M.W : 283.64
SMILES Code : NC1=NC=CC(OC2=CC=C([N+]([O-])=O)C=C2F)=C1Cl

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Application In Synthesis of [ 1415797-76-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1415797-76-0 ]

[ 1415797-76-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 188577-69-7 ]
  • [ 403-19-0 ]
  • [ 1415797-76-0 ]
YieldReaction ConditionsOperation in experiment
16% With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; at 120℃; for 24.0h; <strong>[188577-69-7]3,4-dichloro-2-aminopyridine</strong> (500 mg, 3.07 mmol, prepared with reference to document: Synthetic Communications, 1997, 27(5), 861-870.) and 2-fluoro-4-nitrophenol (1.928 g, 12.27 mmol) were heated to 120 C. and melted, and stirred for 24 hrs. The molten was cooled to room temperature, and subjected to silica gel column chromatography (the eluent was dichloromethane to dichloromethane/methanol=50/1) for purification, to obtain a white solid (137 mg, 16%). 1H NMR (DMSO-d6, 300 MHz) delta 8.38 (dd, 1H, J=10.5, 2.4 Hz), 8.148.09 (m, 1H), 7.86 (d, 1H, J=5.4 Hz), 7.427.36 (m, 1H), 6.60 (br, 2H), 6.27 (d, 1H, J=5.4 Hz).
 

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