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[ CAS No. 1416881-52-1 ]

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Chemical Structure| 1416881-52-1
Chemical Structure| 1416881-52-1
Structure of 1416881-52-1 * Storage: {[proInfo.prStorage]}

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Product Details of [ 1416881-52-1 ]

CAS No. :1416881-52-1 MDL No. :MFCD27939633
Formula : C56H32N6 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :788.89 g/mol Pubchem ID :102198498
Synonyms :

1. 4CzIPN

Safety of [ 1416881-52-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 UN#:N/A
Hazard Statements:H302-H312-H332 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1416881-52-1 ]

  • Upstream synthesis route of [ 1416881-52-1 ]
  • Downstream synthetic route of [ 1416881-52-1 ]

[ 1416881-52-1 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 86-74-8 ]
  • [ 1416881-52-1 ]
YieldReaction ConditionsOperation in experiment
19.7%
Stage #1: With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5 h; Inert atmosphere
Stage #2: at 60℃; for 10 h; Inert atmosphere
480 mg (12.0 mmol) of 60percent sodium hydride was placed in a 100-mE three-neck flask, the interior of the flask was substituted with nitrogen, and 40 mE, of N,N-dimethylformamide was added thereto, followed by stirring. 1.67 g (10.0 mmol) of 9H-carbazole was added to the mixture, which was stirred under a nitrogen stream at room temperature for 30 minutes. Afier stirring, 400 mg (2.00 mmol) of tetrafluoroisophthalonitrile was added to the mixture, and the mixture was stirred under a nitrogen atmosphere at 60° C. for 10 hours. Afier stirring, 5.0 mE of water was added to the mixture, which was then stirred. Afier stirring, N,Ndimethylformamide was removed from the mixture. After the removal, 200 mE of water was added to the mixture, to which ultrasonic waves were applied. Afier the application, the mixture was suction-filtered to provide a solid mattet The resulting solid matter was purified by silica gel colunmchromatography. In the column chromatography, a mixed solvent of chloroform and hexane (1/5) was firstly used as a developing solvent, and then a mixed solvent of chloroform and hexane (1/2) was used as a developing solvent. The resulting fraction was concentrated to provide a solid matter, which was then recrystallized from a mixed solvent of acetone, and hexane, thereby providing a yellow powdered solid matter in a yield amount of 311 mg and a yield of19.7percent.
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[3] Journal of the American Chemical Society, 2017, vol. 139, # 29, p. 9799 - 9802
[4] Organic Letters, 2018, vol. 20, # 18, p. 5533 - 5536
[5] Nature, 2012, vol. 492, # 7428, p. 234 - 238
[6] Angewandte Chemie - International Edition, 2018, vol. 57, # 35, p. 11278 - 11282[7] Angew. Chem., 2018, vol. 130, # 35, p. 11448 - 11452,5
[8] Chemical Science, 2018, vol. 9, # 27, p. 5883 - 5889
[9] Chemical Communications, 2016, vol. 52, # 64, p. 9877 - 9880
[10] Chemical Communications, 2018, vol. 54, # 67, p. 9337 - 9340
[11] Journal of Organic Chemistry, 2015, vol. 80, # 18, p. 9126 - 9131
[12] Chemical Communications, 2018, vol. 54, # 44, p. 5606 - 5609
[13] Patent: US9502668, 2016, B2, . Location in patent: Page/Page column 126; 127
[14] Patent: CN107382910, 2017, A, . Location in patent: Paragraph 0015; 0016
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