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Chemical Structure| 1426143-77-2 Chemical Structure| 1426143-77-2

Structure of 1426143-77-2

Chemical Structure| 1426143-77-2

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Product Details of [ 1426143-77-2 ]

CAS No. :1426143-77-2
Formula : C44H31N4OP
M.W : 662.72
SMILES Code : P(C1C=CC=CC=1)(C1C=CC(C2=NC3=CC=CC=C3N2C2C=CC=CC=2)=CC=1)(C1C=CC(=CC=1)C1=NC2=CC=CC=C2N1C1C=CC=CC=1)=O
MDL No. :N/A
InChI Key :AGKXFVABDARJOX-UHFFFAOYSA-N
Pubchem ID :90049308

Safety of [ 1426143-77-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 1426143-77-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1426143-77-2 ]

[ 1426143-77-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 644-97-3 ]
  • [ 2620-76-0 ]
  • [ 1426143-77-2 ]
YieldReaction ConditionsOperation in experiment
15% Intermediate 1-2 (10 g, 28.6 mmol) in a 500 mL three neck flaskAnd THF (100 mL) were added and stirred for 20 minutes.The reaction mixture was cooled to -78 C. using a cold bath (Acetone / Liq-N2 bath), n-BuLi (2.5 M, 11.9 mL, 29.9 mmol) was added, followed by 2 hours under a nitrogen stream. After stirring dichlorophenylphosphine(dichlorophenylphosphine) (2.32 g, 13.0 mmol) was added thereto, and the temperature was slowly raised, followed by stirring at room temperature for 24 hours. H2O (30 mL) was added to the mixture, and the reaction was terminated. After extraction with CH2Cl2 (500 mL x 2), water was removed using anhydrous MgSO4 and distilled under reduced pressure. The result obtained there from oxidation using CH2Cl2 and 30% H202 followed by column chromatography (MeOH / EA: 1/20) gave compound 1, which was confirmed by 1 H NMR and mass.Yield: 1.22 g, 15%
 

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