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Chemical Structure| 1427556-50-0 Chemical Structure| 1427556-50-0

Structure of 1427556-50-0

Chemical Structure| 1427556-50-0

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Product Details of [ 1427556-50-0 ]

CAS No. :1427556-50-0
Formula : C27H21NO
M.W : 375.46
SMILES Code : CC1(C)C2=C(C3=C1C=CC=C3)C=CC(NC4=CC=C5C(OC6=CC=CC=C56)=C4)=C2
MDL No. :N/A

Safety of [ 1427556-50-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1427556-50-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1427556-50-0 ]

[ 1427556-50-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 26608-06-0 ]
  • [ 108714-73-4 ]
  • [ 1427556-50-0 ]
YieldReaction ConditionsOperation in experiment
80% With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; XPhos; In toluene; at 105 - 110℃; for 2h;Inert atmosphere; <strong>[26608-06-0]3-bromodibenzofuran</strong> (10.0 g, 40.5 mmol),2-bromo-9,9-dimethylhydrazine (9.3 g, 44.5 mmol),Tris(dibenzylideneacetone)dipalladium (0.4 g, 0.4 mmol),2-Dicyclohexylphosphino-2,4,6-triisopropylbiphenyl (0.4 g, 0.8 mmol) and sodium tert-butoxide (5.8 g, 60.7 mmol) were added to toluene (100 mL).Heated to 105-110 C under nitrogen protection,After stirring for 2 hours; cooling to room temperature, the reaction solution was washed twice with water, dried over magnesium sulfate, filtered, and then filtered, and the filtrate was passed through a silica gel column, and the solvent was removed under reduced pressure. The crude product was recrystallized and purified using dichloromethane/n-heptane system. The pale yellow solid intermediate VII-B (12.1 g, 80%) was obtained.
 

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