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Chemical Structure| 1442461-86-0 Chemical Structure| 1442461-86-0

Structure of 1442461-86-0

Chemical Structure| 1442461-86-0

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Product Details of [ 1442461-86-0 ]

CAS No. :1442461-86-0
Formula : C23H14BrN
M.W : 384.27
SMILES Code : BrC1=CC=C(C2=C3C=CC4=CC=CC=C4C3=C(C=CC=C5)C5=N2)C=C1
MDL No. :N/A

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Application In Synthesis of [ 1442461-86-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1442461-86-0 ]

[ 1442461-86-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 952514-79-3 ]
  • [ 1442461-86-0 ]
  • C42H27N3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In ethanol; water; toluene; for 12h;Reflux; The compound is added 187-1 (8.85g, 23 . 0mmol), 1-phenyl -1H-benzo [d] imidazol-2-phenyl boronic acid (11.8g, 29 . 9mmol), Pd (PPh3)4(1.32g, 1 . 15mmol), 2MK2CO3aqueous solution (40 ml), toluene (200 ml) and ethanol (40 ml), and then flows back 12 hours. After the completion of reaction, the resulting reaction product is cooled to the room temperature, distilled water and is then used to extract the EA. Organic layer using an anhydrous MgSO4drying, and the post for rotary evaporimeter to remove the solvent, the use of methylene chloride and hexane as a solvent through the column chromatography purification of the resulting reaction product, to obtain a target compound 187 (8.9g, 68%).
 

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