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Chemical Structure| 144511-93-3 Chemical Structure| 144511-93-3

Structure of 144511-93-3

Chemical Structure| 144511-93-3

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Product Details of [ 144511-93-3 ]

CAS No. :144511-93-3
Formula : C14H10ClN3
M.W : 255.71
SMILES Code : ClC1=NC2=CC=CC=C2C(NC3=CC=CC=C3)=N1
MDL No. :MFCD09726613

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Application In Synthesis of [ 144511-93-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 144511-93-3 ]

[ 144511-93-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 109903-35-7 ]
  • [ 144511-93-3 ]
  • N-methyl-[4-(4-phenylamino-quinazolin-2-ylamino)-phenyl]-methanesulfonamide hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
In i-Amyl alcohol; N-Methyl-[4-(4-phenylamino-quinazolin-2-ylamino)-phenyl]-methanesulfonamide hydrochloride A solution of 2-chloro-4-phenylamino-quinazoline (0.92 g) (prepared as described in Example 1a and N-methyl-(4-aminophenyl)-methanesulfonamide (0.80 g) in 10 ml of isopentylalcohol is stirred under nitrogen at 170 C. for 15 min in a sealed vessel. The warm reaction mixture is diluted with 10 ml ethanol and the hydrochloride salt, which is crystallizing on cooling, is filtered off to yield N-methyl-[4-(4-phenylamino-quinazolin-2-ylamino)-phenyl]-methanesulfonamide hydrochloride as light yellow crystals melting at 259-263 C.; Rf (A2) 0.11, FAB-MS: (M+H)+ =420. Analytical data: C22 H21 N5 O2 S+HCl.
  • 2
  • [ 28466-26-4 ]
  • [ 144511-93-3 ]
  • N<SUP>4</SUP>-phenyl-N<SUP>2</SUP>-(1H-pyrazol-4-yl)quinazoline-2,4-diamine [ No CAS ]
 

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