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Chemical Structure| 1447947-87-6
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Product Details of [ 1447947-87-6 ]

CAS No. :1447947-87-6 MDL No. :MFCD32670809
Formula : C39H48B3N3O6 Boiling Point : -
Linear Structure Formula :- InChI Key :QHDOUYVNUGDLTI-UHFFFAOYSA-N
M.W : 687.25 Pubchem ID :138958484
Synonyms :

Safety of [ 1447947-87-6 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1447947-87-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1447947-87-6 ]

[ 1447947-87-6 ] Synthesis Path-Downstream   1~22

  • 1
  • [ CAS Unavailable ]
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
31.1% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; toluene for 48h; Reflux; Inert atmosphere;
  • 2
  • [ CAS Unavailable ]
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
30.2% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; toluene for 48h; Reflux; Inert atmosphere;
  • 3
  • [ 61676-62-8 ]
  • [ 30363-03-2 ]
  • 2,4,6-tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)[1,3,5]triazine [ No CAS ]
  • 4
  • [ 1447947-87-6 ]
  • [ 1644493-68-4 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
68% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; toluene for 48h; Reflux; Inert atmosphere; 2.2.4. Synthesis of TDPP-TPA Compound 5 (3.35 g, 3.5 mmol), compound 8 (0.68 g, 1 mmol), and tetrakis(triphenylphosphine) palladium (0) (Pd(PPh3)4 0.16 g,0.138 mmol) were dissolved in a mixture of toluene and aqueous K2CO3 (2 M, 10 mL). The solution was heated under reflux with vigorous stirring under a nitrogen atmosphere for 48 h. After cooling to room temperature, the solution was partitioned between DCM and water. The organic phase was collected, dried (MgSO4), filtered, and evaporated to dryness. The crude product was purified by column chromatography on silica gel with ethyl acetate(AcOEt):n-hexane (1:30) as the eluant to give black purple solid (compound TDPPTPA) (2.0 g, yield 68%). Tm was 298 °C. FTIR (KBr, cm-1): 2800-3000 (C-H), 1668 (C=O), 1598, 1562, 1507, 1498, 1438, 1400(amide, C-N), 1260-1350 (aromatic amine, C-N), 1235, 1195, 1105,1090, 1030, 970, 830, 810, 790. 1H NMR (600 MHz, CDCl3, TMS) :δ 0.85 (s, 54H), 1.21-1.44 (m, 84H), 1.80-2.10 (m, 6H), 4.07-4.14 (m,12H), 7.04-7.10 (m, 18H), 7.27 (d, J 12.0 Hz, 12H), 7.36 (d,J 6.0 Hz, 3H), 7.46-7.52 (m, 9H), 7.67-7.80 (m, 12H), 8.95 (d,J 6.0 Hz, 3H), 9.02 (d, J 6.0 Hz, 3H).13C NMR (150 MHz, CDCl3): 10.6, 14.1, 23.1, 23.6, 28.50, 29.7, 30.3, 31.4, 34.4, 39.2, 46.0, 116.8,122.3, 124.5, 126.2, 126.7, 127.6, 128.0, 129.2, 130.1, 130.7, 132.2,133.6, 144.6, 146.2, 146.4, 147.4, 148.4, 149.0, 162.5, 162.9, 171.1 162.7. Anal. Calcd for C192H216N12O6S6: C, 77.42; H, 7.26; N, 5.65; S, 6.45. Found:C, 77.39; H, 7.28; N, 5.57; S, 6.48
  • 5
  • [ 1447947-87-6 ]
  • [ 1644493-74-2 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
69% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; toluene for 48h; Reflux; Inert atmosphere; 2.2.4. Synthesis of PDPP-TPA Compound 6 (3.11 g, 3.5 mmol), compound 8 (0.68 g, 1 mmol), and tetrakis(triphenylphosphine) palladium (0) (Pd(PPh3)4 0.16 g,0.138 mmol) were dissolved in a mixture of toluene and aqueous K2CO3 (2 M, 10 mL). The solution was heated under reflux with vigorous stirring under a nitrogen atmosphere for 48 h. After cooling to room temperature, the solution was partitioned between DCM and water. The organic phase was collected, dried (MgSO4), filtered, and evaporated to dryness. The crude product was purified by column chromatography on silica gel with ethyl acetate(AcOEt):n-hexane (1:30) as the eluant to give a dark red solid (compound PDPPTPA) (1.88 g, yield 69%). Tm was not detectable. FTIR (KBr, cm-1): 2800-3000 (C-H), 1670 (C=O), 1600, 1510, 1490, 1460,1400 (amide, C-N), 1360, 1320, 1260e1300 (aromatic amine, C-N),1095, 1000, 820, 670. 1H NMR (600 MHz, CDCl3, TMS) :0.84 (t,J 4.8 Hz, 18H), 1.25-1.27 (m, 36H), 1.33 (s, 54H), 1.64-1.71 (m,12H), 3.83 (s, 12H), 7.10 (d, J 8.4 Hz, 12H), 7.13 (d, J 8.4 Hz, 6H),7.30 (d, J 9.0 Hz, 12H), 7.52 (d, J 8.4 Hz, 6H), 7.73 (d, J 8.4 Hz,6H), 7.78 (s, 12H), 7.83 (d, J 8.4 Hz, 6H), 7.92 (d, 6H), 7.96 (d,J 8.4 Hz, 6H). 13C NMR (150 MHz, CDCl3): δ 13.9, 22.5, 26.4, 29.4,31.2, 31.4, 34.3, 41.9, 42.1, 124.5, 126.2, 127.1, 128.0, 128.4, 129.2,129.6, 130.1, 131.6, 132.2, 135.7, 136.5, 143.6, 144.6, 146.2, 146.4,147.4,148.4,149.0,162.5,162.9,171.5. Anal. Calcd for C189H204N12O6: C, 82.89; H, 7.46; N, 6.14. Found: C, 82.84; H, 7.49; N, 6.11.
  • 6
  • [ 1447947-87-6 ]
  • [ 1644493-79-7 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
70% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; toluene for 48h; Reflux; Inert atmosphere; 2.2.4. Synthesis of PDPP-TPA Compound 7 (3.10 g, 3.5 mmol), compound 8 (0.68 g, 1 mmol),and tetrakis(triphenylphosphine) palladium (0) (Pd(PPh3)4 0.16 g,0.138 mmol) were dissolved in a mixture of toluene and aqueous K2CO3 (2 M, 10 mL). The solution was heated under reflux with vigorous stirring under a nitrogen atmosphere for 48 h. After cooling to room temperature, the solution was partitioned between DCM and water. The organic phase was collected, dried (MgSO4), filtered, and evaporated to dryness. The crude product was purified by column chromatography on silica gel with ethyl acetate(AcOEt):n-hexane (1:30) as the eluant to give a dark red solid (compound PDPP-Cz) ((1.91 g, yield=70%).%). Tm 323.0 °C. FTIR (KBr, cm-1): 2800-3000 (C-H), 1679 (C=O), 1605, 1500, 1490, 1475, 1395(amide, C-N), 1360, 1325, 1260-1300 (carbazole, C-N), 1095, 1000,815, 735. 1H NMR (600 MHz, CDCl3, TMS) δ 0.82-0.87 (t, J 6.6 Hz,18H), 1.23-1.28 (m, 36H), 1.46 (s, 54H), 1.64-1.70 (m, 12H),3.81-3.88 (t, J 6.0 Hz, 12H), 7.43 (d, J 8.4 Hz, 6H), 7.47 (d,J 7.2 Hz, 6H), 7.67 (d, J 8.4 Hz, 6H), 7.83 (s, 12H), 7.82 (d,J 8.4 Hz, 6H), 7.85 (dd, J 6.0 Hz, 12H), 7.96 (dd, J 7.8 Hz, 12H),8.14 (s, 6H). 13C NMR (150 MHz, CDCl3): δ 14.0, 22.5, 26.5, 29.5, 29.7,31.3, 32.0, 34.7, 42.1, 109.3, 110.0, 116.3, 123.5, 123.7, 127.0, 127.2,127.4, 127.6, 128.4, 129.4, 138.2, 138.3, 139.0, 140.1, 142.9, 143.0,143.2, 148.0, 148.1, 162.8, 171.4. Anal. Calcd for C189H204N12O6: C,83.08; H, 7.25; N, 6.15. Found: C, 82.99; H, 7.28; N, 6.18.
  • 7
  • [ 30363-03-2 ]
  • [ 73183-34-3 ]
  • 2,4,6-tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)[1,3,5]triazine [ No CAS ]
  • 8
  • [ 1447947-87-6 ]
  • [ 2020323-96-8 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
48% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran at 85℃; for 24h; Inert atmosphere;
  • 9
  • [ CAS Unavailable ]
  • [ 1447947-87-6 ]
  • [ 2088666-53-7 ]
YieldReaction ConditionsOperation in experiment
24% With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate In tetrahydrofuran; water for 72h; Inert atmosphere; Reflux; 3.1.1 Synthesis of compound 4 In a 200mL two-necked flask was placed 0.6270g (0.912mmol) of 2 and 2.4078g (4.40mmol) of 4-(5-bromo-3-hexylthiophen-2-yl)-7-(3-hexylthiophen-2-yl)benzo[c][1,2,5]thiadiazol (3) and 0.8927 g (2.74 mmol) of cesium carbonate and 0.0676cg (0.0963mmol) of bis(triphenylphosphine)dichloropalladium in 75mL of THF and 15mL of H2O. After the mixture was heated to reflux for 3 days, it was hydrolyzed with dilute hydrochloric acid. The organic layer was separated, washed with water, and dried over anhydrous magnesium sulfate. After the solvent was evaporated, compound 4 (0.3743g, 24% yield) was isolated by a silica gel column eluting with hexane-ethyl acetate (50:1) as a red solid: M.p. 75-76°C. HRMS (ESI) exact mass calcd for C99H106N9S9 (M++H): 1708.60521, found 1708.60650. MS m/z 1707 (M+); 1H NMR (δ CDCl3) 0.83 (t, 9H, CH3, J=7.4Hz), 0.85 (t, 9H, CH3, J=7.4Hz), 1.21-1.32 (m, 36H, CH2), 1.65 (quint, 6H, CH2, J=7.4Hz), 1.72 (quint, 6H, CH2, J=7.4Hz), 2.69 (t, 6H, CH2, J=7.4Hz), 2.74 (t, 6H, CH2, J=7.4Hz), 7.12 (d 3H, thienylene protons, J=5.2Hz), 7.46 (d, 3H, thienylene protons, J=5.2Hz), 7.52 (s, 3H, thienylene protons), 7.69 (d, 3H, phenylene protons, J=7.6Hz), 7.73 (d, 3H, phenylene protons, J=7.6Hz), 7.90 (d, 6H, phenylene protons, J=8.8Hz), 8.83 (d, 6H, phenylene protons, J=8.8Hz); 13C NMR (δ CDCl3) 13.9 (2C) (CH3), 22.4, 22.5, 29.0, 29.1, 29.3, 29.6, 30.5 (2C), 31.4 (2C) (CH2), 125.2, 125.8, 126.3, 126.9, 127.4, 129.1, 129.3, 129.5, 129.7, 132.1, 132.9, 135.0, 137.6, 141.5, 142.9, 143.5, 153.8, 154.1, 170.4 (thienylene and phenylene carbons).
  • 10
  • [ 30363-03-2 ]
  • [ 76347-13-2 ]
  • 2,4,6-tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)[1,3,5]triazine [ No CAS ]
  • 11
  • [ 1447947-87-6 ]
  • [ 2102525-74-4 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
41% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran for 24h; Reflux; Inert atmosphere; 2.6. Synthesis of p-TPA-TPE and m-TPA-TPE General procedure: A mixture of compound 4 (4 mol eq), compound 5 or 6 (1 mol eq), tetrakis(triphenylphosphine)palladium (0.03 mol eq), potassium carbonate solution (2 M, 15 mL) and THF (45 mL) was refluxed for 24 h under nitrogen. After cooling to room temperature, the mixture was poured into water and extracted with CH2Cl2 (3 x 10 mL). The organic phase was washed with water for three times and dried with anhydrous Na2SO4. The solvent was removed under vacuum, and then the residue was purified by column chromatography with PE/CH2Cl2 (2:1) as an eluent to get the targetcompounds. p-TPA-TPE: Light green solid. Yield: 41%. 1H NMR (400 MHz,CDCl3), δ: 8.83 (d, J = 8.4 Hz, 6H), 7.92 (dd, J = 7.6 Hz, 14.8 Hz, 6H),7.84-7.62 (m, 24H), 7.54 (d, J = 7.6 Hz, 6H), 7.37 (d, J = 8.4 Hz, 6H),7.14-7.07 (m, 60H), 6.65 (t, J = 7.6 Hz, 6H), 6.58 (d, J = 8.0 Hz, 6H),6.43 (d, J = 7.6 Hz, 6H); 13C NMR (101 MHz, CDCl3), δ: 171.31, 157.50,157.18, 143.79, 141.28, 131.83, 131.37, 130.08, 129.44, 128.02, 127.61,126.46, 120.76, 120.60, 114.79, 77.23, 77.03, 76.71, 57.20 ppm. TOFMS(EI): m/z: calcd for C192H126N6: 2515.004 [M+]; found: 2515.823. CHN: calcd for C192H126N6, C, 91.62; H, 5.05; N, 3.34%;found: C 91.39, H 5.14, N 3.17%.
  • 12
  • [ 1241891-64-4 ]
  • 2,4,6-tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)[1,3,5]triazine [ No CAS ]
  • C114H72N6 [ No CAS ]
YieldReaction ConditionsOperation in experiment
45% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran for 24h; Inert atmosphere; Reflux; 2.5. Synthesis of p-TPA and m-TPA General procedure: A mixture of compound 1 or 2 (4 mol eq), compound 5 or 6 (1 mol eq), tetrakis(triphenylphosphine)palladium (0.03 mol eq), potassium carbonate solution (2 M, 15 mL) and THF (45 mL) was refluxed for 24 h under nitrogen. After cooling to room temperature, the mixture was poured into water and extracted with CH2Cl2 (3 x 20 mL). The organic phase was washed with water (3 x 20 mL)and dried with anhydrous Na2SO4. The solvent was removed under vacuum, and then the residue was purified by column chromatographyusing PE/CH2Cl2 (2:1) as an eluent to get the target compounds. p-TPA: Light yellow solid. Yield: 45%. 1H NMR (400 MHz, CDCl3), δ: 8.83 (d, J = 8.0 Hz, 6H), 7.95 (d, J = 8.0 Hz, 6H), 7.87 (t, J = 9.2 Hz,6H), 7.77-7.62 (m, 12H), 7.58-7.50 (m, 12H), 7.44 (t, J = 7.2 Hz, 7.33), (t, J = 8 Hz, 3H), 6.96 (t, J = 8.0 Hz, 6H), 6.64 (t, J = 8.0 Hz, 6H),6.54 (d, J = 7.6 Hz, 6H), 6.43 (d, J = 8.2 Hz, 6H); 13C NMR (101 MHz,CDCl3), δ: 171.29, 157.18, 156.79, 145.17, 141.43, 141.07, 140.48,139.42, 138.61, 135.11, 131.19, 129.42, 128.59, 127.72, 127.36, 127.15,125.86, 124.78, 124.57, 120.70, 120.38, 120.17, 114.76, 77.36, 77.05,76.73, 57.10 ppm; TOF-MS (EI): m/z: calcd for C114H72N6: 1524.582[M]; found: 1525.000. CHN: calcd for C114H72N6, C, 89.74; H, 4.76;N, 5.51%; found: C 89.40, H 4.81, N 5.70%.
  • 13
  • [ 523-27-3 ]
  • [ 1447947-87-6 ]
  • [ 1447947-88-7 ]
YieldReaction ConditionsOperation in experiment
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tris-(o-tolyl)phosphine In N,N-dimethyl-formamide
  • 14
  • [ 1015473-19-4 ]
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
70% With tetrakis(triphenylphosphine) palladium(0); potassium acetate In water at 120℃; for 24h; Inert atmosphere; 2.2.5. TPDI A mixture of 2 (87 mg, 0.12 mmol), 4 (28 mg, 0.04 mmol), tetrakis(triphenylphosphine)palladium (19 mg), aqueous KOAc (2 M, 2.5 mL),and toluene (15 mL) was stirred at 120 °C for 24 h under a N2 atmosphere.After cooling to room temperature, the mixture was partitionedbetween CH2Cl2 and deionized water; the aqueous phase was extractedseveral times with CH2Cl2. The combined organic phases were washedwith deionized water, dried (anhydrous MgSO4). and poured intoMeOH. The precipitate was filtered off, washed with MeOH, and driedunder vacuum for 4 h to give a deep-purple solid (60 mg, 70%). FTIR(KBr, cm-1): 2921-2859 (C-H), 1699 (C]N), 1656 (C]O), 1585, 1511(C-N), 1450, 1344, 1248 (C-H), 1098, 804, 747. Figure S1:1H NMR (δ/ppm, 600 MHz, CDCl3): 8.98 (d, J=7.8 Hz, 6H), 8.80 (d, J=8.4 Hz,3H), 8.65 (d, J=7.8 Hz, 6H), 8.16 (d, J=7.2 Hz, 3H), 8.08 (s, 3H),7.96-8.03 (m, 6H), 7.74 (d, J=7.8 Hz, 6H), 4.01-4.25 (m, 12H),1.85-2.00 (m, 6H), 1.12-1.47 (m, 48H), 0.78-0.95 (m, 36H). Figure S2:13C NMR (δ/ppm, 150 MHz, CDCl3): 163.82, 134.65, 131.53, 131.21,130.09, 129.05, 128.46, 123.30, 123.13, 119.95, 110.00, 96.102,30.75, 30.03, 29.69, 28.70, 24.07, 23.07, 22.69, 14.12, 10.65. FigureS3: MALDI-TOF-MS: Calcd for C141H135N9O12: m/z 2146.0230 [M+];found: 2147.6307.
  • 15
  • [ 30363-03-2 ]
  • 2,4,6-tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)[1,3,5]triazine [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; bis(pinacol)diborane; In 1,4-dioxane; for 24h;Reflux; Inert atmosphere; A mixture of 3 (1.20 g, 2.20 mmol), bis(pinacolato)diboron (1.90 g,7.30 mmol), KOAc (0.600 g, 6.60 mmol), and PdCl2(dppf) (0.100 g,0.140 mmol) in 1,4-dioxane (50 mL) was heated under reflux for 24 hunder a N2 atmosphere. After cooling to room temperature, the mixturewas poured into deionized water and extracted with CH2Cl2. The organicphase was dried (MgSO4), filtered, and evaporated to dryness.The residue was purified chromatographically (SiO2; petroleum ether/CH2Cl2=1:1) to provide a white solid (1.13 g, 75.0%). FTIR (KBr,cm-1): 2977-2927 (C-H), 1570, 1507, 1337 (B-O), 1272, 1144 (B-C),1087 (C-O), 867, 818, 648.1H NMR (delta/ppm, 600 MHz, CDCl3): 8.74 (d,6H, J=8.4 Hz), 7.99 (d, 6H, J=8.4 Hz), 1.38 (s, 36H). Anal. Calcd forC39H48O6N3B3: C, 68.18; H, 7.00; O, 13.98; N, 6.12; Br, 4.72. Found: C,68.14; H, 7.02; O, 13.95; N, 6.15; Br, 4.74.
  • 16
  • [ 1447947-87-6 ]
  • [ 2451364-74-0 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux
  • 17
  • [ 1447947-87-6 ]
  • [ 2451364-75-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux
  • 18
  • [ 1447947-87-6 ]
  • [ 2451364-76-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux
  • 19
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2.1: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux 3.1: hydrogenchloride / toluene; 1,4-dioxane / 18 h / 43 °C / Inert atmosphere; Schlenk technique 3.2: 8 h / 20 °C / Inert atmosphere; Schlenk technique
  • 20
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2.1: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux 3.1: hydrogenchloride / toluene; 1,4-dioxane / 18 h / 43 °C / Inert atmosphere; Schlenk technique 3.2: 8 h / 20 °C / Inert atmosphere; Schlenk technique
  • 21
  • [ 1447947-87-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 24 h / 90 °C / Inert atmosphere; Schlenk technique 2.1: acetic acid / chloroform; ethanol / 16 h / Inert atmosphere; Schlenk technique; Reflux 3.1: hydrogenchloride / toluene; 1,4-dioxane / 24 h / 43 °C / Inert atmosphere; Schlenk technique 3.2: 8 h / 20 °C / Inert atmosphere; Schlenk technique
  • 22
  • [ 31181-90-5 ]
  • [ 1447947-87-6 ]
  • [ 2451364-73-9 ]
YieldReaction ConditionsOperation in experiment
40% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In N,N-dimethyl-formamide at 90℃; for 24h; Inert atmosphere; Schlenk technique;
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