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Chemical Structure| 14572-92-0 Chemical Structure| 14572-92-0

Structure of 14572-92-0

Chemical Structure| 14572-92-0

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Product Details of [ 14572-92-0 ]

CAS No. :14572-92-0
Formula : C9H13NO
M.W : 151.21
SMILES Code : OCCCC1=CC=C(N)C=C1
MDL No. :MFCD09028722
InChI Key :VTHAHSYNSNZPSI-UHFFFAOYSA-N
Pubchem ID :220424

Safety of [ 14572-92-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 14572-92-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14572-92-0 ]

[ 14572-92-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35418-07-6 ]
  • [ 14572-92-0 ]
YieldReaction ConditionsOperation in experiment
66.7% With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20℃; A cold solution of Methyl 3-(4-aminophenyl)propionate obtained in preparation 16 (0.48 g, 2.7 mmol) in THF (10 mL) was slowly added drop wise to a suspension of LAH (132 mg, 3.49 mmol) in THF (10 mL) at 0 C. and stirred for overnight at room temperature. Unreacted LAH was quenched with satd. Na2SO4 solution and filtered through celite and the bed was thoroughly washed with ethyl acetate. The filtrate and the washings were combined and the organic layer was dried (Na2SO4) and evaporated. The residue on purification yielded the title compound (0.27 g, 66.7%) as yellow solid. [0262] Mp: 54-56 C. [0263] 1H NMR (200 MHz, CDCl3): delta 1.88-1.92 (m, 2H); 2.60 (t, J=7.5 Hz, 2H); 3.66 (t, J=6.3 Hz, 2H); 6.63 (d, J=8.1 Hz, 2H); 6.99 (d, J=8.1 Hz, 2H). [0264] Mass m/z (CI): 152 [M+1].
 

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