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Chemical Structure| 1478-01-9 Chemical Structure| 1478-01-9

Structure of 1478-01-9

Chemical Structure| 1478-01-9

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Product Details of [ 1478-01-9 ]

CAS No. :1478-01-9
Formula : C12H8FNO2
M.W : 217.20
SMILES Code : O=N(=O)C=1C=CC(F)=CC1C=2C=CC=CC2
MDL No. :MFCD14701891

Safety of [ 1478-01-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 1478-01-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1478-01-9 ]

[ 1478-01-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1255308-97-4 ]
  • [ 1478-01-9 ]
  • [ 1448304-71-9 ]
YieldReaction ConditionsOperation in experiment
100% After mixing <strong>[1255308-97-4]5H-[1]benzothieno[3,2-c]carbazole</strong> (8.8 g, 40.5 mmol) and DMF 180 mL, NaH (1.9 g, 60% dispersion in mineral oil, 49 mmol) was added to the mixture while stirring, and then the mixture was stirred for 30 minutes. Then, a solution in which compound 5-1 (11 g, 16.5 mmol) dissolved in DMF 20 mL, was slowly added dropwise to the reaction mixure. Then, the mixture was stirred for 4 hours at room temperature. After completing the reaction, the mixture was washed with distilled water, and then extracted with EA. The organic layer was dried with MgSO4, and solvent was removed with a rotary evaporator. Then, the remaining product was purified by column chromatography using MC and hexane as developing solvents to obtain, yellow solid, compound 5-2 (19 g, 100 %).
 

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