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Chemical Structure| 148580-01-2 Chemical Structure| 148580-01-2

Structure of 148580-01-2

Chemical Structure| 148580-01-2

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Product Details of [ 148580-01-2 ]

CAS No. :148580-01-2
Formula : C27H26N2O17
M.W : 650.50
SMILES Code : O=C(OCC1=CC=C(O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](C(OC)=O)O2)C([N+]([O-])=O)=C1)OC3=CC=C([N+]([O-])=O)C=C3

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Application In Synthesis of [ 148580-01-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 148580-01-2 ]

[ 148580-01-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 474645-27-7 ]
  • [ 148580-01-2 ]
  • C60H88N6O21 [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With pyridine; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20℃; for 48h;Inert atmosphere; MMAE (25mg, 0.035mmol) and carbonate 4 (23mg, 0.035mmol) were dissolved in dry DMF (800muL) and pyridine (200muL). HOBt (4.7mg, 0.035mmol) and DIPEA (7.3muL, 0.042mmol) were added. The mixture was stirred at room temperature. After 48h, solvents were removed under reduced pressure and the crude material was purified by preparative TLC over silica gel (CH2Cl2/MeOH, 97/3) to afford 5 (29mg, 68percent) as a white solid (retention time=22.6min for HPLC analysis (method A)).
 

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