Alternatived Products of [ 148673-39-6 ]
Product Details of [ 148673-39-6 ]
CAS No. : | 148673-39-6 |
MDL No. : | MFCD22376836 |
Formula : |
C10H10ClNO3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
227.64
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 148673-39-6 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 148673-39-6 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 148673-39-6 ]
- 1
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[ 67-56-1 ]
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[ 134372-47-7 ]
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[ 148673-39-6 ]
- 2
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[ 139329-90-1 ]
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[ 148673-39-6 ]
- 3
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[ 134372-47-7 ]
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[ 148673-39-6 ]
Yield | Reaction Conditions | Operation in experiment |
|
With sulfuric acid; sodium hydrogencarbonate; In methanol; ethyl acetate; |
REFERENCE EXAMPLE 1 A mixture of 12 g of <strong>[134372-47-7]6-chloro-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid</strong>, 200 ml of methanol, and 10 ml of concentrated sulfuric acid was heat-refluxed for 24 hours with stirring. The liquid reaction mixture was concentrated in vacuo. To the residue were added an aqueous solution of sodium hydrogencarbonate and ethyl acetate, and the resulting organic layer was separated, washed with water, and dried over magnesium sulfate. The solvent was clitilled off under reduced pressure, and the residue was recrystallized from a mixed solvent of isopropyl ether and ethanol to give 9.2 g of methyl 6-chloro-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylate. Melting point: 60-61 C. |