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Chemical Structure| 149485-85-8 Chemical Structure| 149485-85-8

Structure of 149485-85-8

Chemical Structure| 149485-85-8

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Product Details of [ 149485-85-8 ]

CAS No. :149485-85-8
Formula : C7H6N4S2
M.W : 210.28
SMILES Code : S=C(N1C=CN=C1)NC2=NC=CS2
MDL No. :MFCD23103197

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Application In Synthesis of [ 149485-85-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 149485-85-8 ]

[ 149485-85-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14173-40-1 ]
  • [ 149485-85-8 ]
  • N-[(2-thiazolyl)amino]thioxomethyl-DL-4-chlorophenylalanine methyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
840 mg (20%) In N-methyl-acetamide; Example 261 N-[(2-thiazolyl)amino]thioxomethyl-DL-4-chlorophenylalanine methyl ester A solution of 1-[(2-thiazolyl)thiocarbamoyl]imidazole (1.5 g, 7.1 mmol) and DL-4-chlorophenylalanine methyl ester hydrochloride (1.78 g, 7.1 mmol) in dimethylformamide (65 mL) was heated at 80 C. for 6 h. The reaction was cooled to room temperature, the solvent removed under reduced pressure, and the residue recrystallized from ethyl ether-hexanes to provide 840 mg (20%) of the titled product: IR (KBr, cm-1) 3176, 3025, 1735, 1562, 1510, 1493, 1467, 1452, 1387, 1353, 1306, 1202, 1191; 1 H NMR (300 MHz, DMSO-d6) delta11.81 (br s, 1H), 7.39 (m, 3H), 7.26 (d, 2H), 7.18 (br s, 1H), 5.09 (q, 1H), 3.64 (s, 3H), 3.18 (m, 2H); MS (FD) m/e 355 (M+);
 

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