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Chemical Structure| 150058-63-2 Chemical Structure| 150058-63-2

Structure of 150058-63-2

Chemical Structure| 150058-63-2

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Product Details of [ 150058-63-2 ]

CAS No. :150058-63-2
Formula : C12H20BrNOSi
M.W : 302.28
SMILES Code : BrC1=CC=CC(CO[Si](C)(C(C)(C)C)C)=N1

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Application In Synthesis of [ 150058-63-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 150058-63-2 ]

[ 150058-63-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5400-79-3 ]
  • [ 150058-63-2 ]
  • C20H33NO4Si [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% n-BuLi (2.5M in hexanes, 1.2 mL, 3 mmol) was added to a -78 C solution ofbromide (903 mg, 3 mmol) in THF (5 mL). The resulting mixture was stirred at -78 C for 30 minutes before a solution the ketone (460 tL, 3 mmol) was added. After an additional hour, the reaction was quenched with NH4C1(sat.). Chromatography over silica gel (hexanes /EtOAc 95:5 to 85:15) afforded the tertiary alcohol (680 mg, 60%).
 

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