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Chemical Structure| 15057-43-9 Chemical Structure| 15057-43-9

Structure of 15057-43-9

Chemical Structure| 15057-43-9

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Product Details of [ 15057-43-9 ]

CAS No. :15057-43-9
Formula : C12H13NO2
M.W : 203.24
SMILES Code : O=C1CN(CC2=CC=CC=C2)CC(O)=C1
MDL No. :MFCD30290472

Safety of [ 15057-43-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 15057-43-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15057-43-9 ]

[ 15057-43-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5779-93-1 ]
  • [ 15057-43-9 ]
  • [ 14205-39-1 ]
  • 4-(2,3-dimethylphenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-7-(phenylmethyl)-1,7-naphthyridine-3-carboxylic acid methyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
In methanol; ethanol; EXAMPLE 20 4-(2,3-dimethylphenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-7-(phenylmethyl)-1,7-naphthyridine-3-carboxylic acid methyl ester A mixture of 16.2 g. of 1-benzyl-3-oxo-5-hydroxy-1,2,3,6-tetrahydropyridine, 9.2 g. of methyl-3-aminocrotonate, 11.6 g. of <strong>[5779-93-1]2,3-dimethylbenzaldehyde</strong> and 180 ml. of ethanol was heated at reflux for 3 hours. The solvent was removed in vacuo and the residue was recrystallized from ethanol to obtain 14 g. of solid, m.p. 208°-211° C. The solid was suspended in methanol and saturated with hydrogen chloride. The solvent was removed in vacuo. The residue was recrystallized from methanol to obtain the title compound as the hydrochloride, m.p. 238°-239° C. d. Analysis for: C26 H28 N2 O3.HCl: Calculated: C, 68.94; H, 6.45; N, 6.18; Cl, 7.83. Found: C, 68.78; H, 6.51; N, 6.41; Cl, 7.77.
 

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