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Chemical Structure| 15536-75-1 Chemical Structure| 15536-75-1

Structure of 15536-75-1

Chemical Structure| 15536-75-1

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Product Details of [ 15536-75-1 ]

CAS No. :15536-75-1
Formula : C3H7NOS
M.W : 105.16
SMILES Code : S=C(N)COC
MDL No. :MFCD02101217

Safety of [ 15536-75-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H351-H412
Precautionary Statements:P201-P202-P264-P270-P273-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P337+P313-P362-P405-P501

Application In Synthesis of [ 15536-75-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15536-75-1 ]

[ 15536-75-1 ] Synthesis Path-Downstream   1~1

  • 1
  • ethyl chloroformyl acetate [ No CAS ]
  • [ 75-34-3 ]
  • [ 15536-75-1 ]
  • [ 33142-21-1 ]
  • [ 59855-95-7 ]
YieldReaction ConditionsOperation in experiment
Step a ethyl 2-methoxymethyl-thiazole-5-carboxylate A mixture of 12.61 g of 2-methoxy-thioacetamide and 150 ml dichloroethane was heated to distill off 10 ml of solvent and after the addition of 18 g ethyl alpha-formyl-chloroacetate, the mixture was refluxed for 3 hours. 5.7 g of ethyl chloroformyl acetate were added and the mixture was refluxed for 2 more hours and was then cooled. The mixture was washed with a sodium bicarbonate solution and then with water, was dried and evaporated to dryness to obtain 27.6 g of raw product. The latter was chromatographed over silica gel and was eluted with an 8-2 benzene-ethyl acetate mixture to obtain 22.5 g of ethyl 2-methoxymethyl-thiazole-5-carboxylate.
 

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