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Chemical Structure| 1564-49-4 Chemical Structure| 1564-49-4

Structure of 1564-49-4

Chemical Structure| 1564-49-4

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Product Details of [ 1564-49-4 ]

CAS No. :1564-49-4
Formula : C7H9N3O4
M.W : 199.16
SMILES Code : CCOC(=O)C1=NC=C(N1C)[N+]([O-])=O
MDL No. :MFCD03789116
InChI Key :IFMBEWCVGFBHPO-UHFFFAOYSA-N
Pubchem ID :2758877

Safety of [ 1564-49-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 1564-49-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 1564-49-4 ]

[ 1564-49-4 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 30148-21-1 ]
  • [ 1564-49-4 ]
YieldReaction ConditionsOperation in experiment
34.7% at 70℃; for 3 h; Step 6a. A solution of ethyl 1 -methyl- lH-imidazole-2-carboxy late (2.0 g, 13 mmol) in 8 ml cone. H2SO4 and 8 ml cone. HNO3 was stirred for 3 hours at 70°C. The solution was diluted with H2O, then adjusted to pH 7-8 with aq Na2C03 solution and extracted with DCM. The organic layer was concentrated and chromatographed (silica, ethyl acetate/petroleum ether) to give the desired compound as yellow solid (0.9g, 34.7percent). ESI- MS m/z = 200.20 [M+H]+
References: [1] Patent: WO2016/183266, 2016, A1, . Location in patent: Page/Page column 50.
  • 2
  • [ 30148-21-1 ]
  • [ 109012-23-9 ]
  • [ 109012-22-8 ]
  • [ 1564-49-4 ]
References: [1] Journal of Organic Chemistry, 1987, vol. 52, # 16, p. 3493 - 3501.
 

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