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Chemical Structure| 15851-87-3 Chemical Structure| 15851-87-3

Structure of 15851-87-3

Chemical Structure| 15851-87-3

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Product Details of [ 15851-87-3 ]

CAS No. :15851-87-3
Formula : C13H11ClO4
M.W : 266.68
SMILES Code : O=C(C1=CC2=CC=C(Cl)C=C2)OC(C)(C)OC1=O

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Application In Synthesis of [ 15851-87-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15851-87-3 ]

[ 15851-87-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 15851-87-3 ]
  • [ 54030-56-7 ]
  • 5-(4-chlorophenyl)-3,4,5,6,7,8-hexahydro-3-methyl-2-methylthiopyrido[2,3-d]pyrimidine-4,7-dione [ No CAS ]
  • 2
  • [ 15851-87-3 ]
  • [ 95-54-5 ]
  • [ 1019-85-8 ]
YieldReaction ConditionsOperation in experiment
90% In ethanol; for 4h;Reflux; General procedure: To a magnetically stirred solution of 1,2-phenylenediamine 1(1.0 mmol) or 1,8-diaminonaphthalene 2 (1.0 mmol) in ethanol (5 mL)was added dropwise arylidene Meldrum’s acid 3 (2.0 mmol) in ethanol (5 mL) at room temperature over 5 min. The reaction mixture was then stirred at reflux conditions for an appropriate time. After completion of the reaction, determined by TLC, the solvent was removed under reduced pressure and the resulting crude product was recrystallised from water to give the pure compounds 4a-k and 5a-i. For the preparation of 4e and 5a, after removal of the solvent, the mixture of products was separated by chromatography on silica gel plates using hexane/ethyl acetate (2:1) to give 9a and 9b as well as 4e and 5a.
 

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