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Chemical Structure| 1608-24-8 Chemical Structure| 1608-24-8

Structure of 1608-24-8

Chemical Structure| 1608-24-8

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Product Details of [ 1608-24-8 ]

CAS No. :1608-24-8
Formula : C9H8F2O
M.W : 170.16
SMILES Code : COC1=CC=C(C=C(F)F)C=C1

Safety of [ 1608-24-8 ]

Application In Synthesis of [ 1608-24-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1608-24-8 ]

[ 1608-24-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 18362-64-6 ]
  • [ 1608-24-8 ]
  • 1-(2-isopropyl-5-(4-methoxyphenyl)furan-3-yl)-2-methylpropan-1-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% With copper(l) iodide; caesium carbonate; In dimethyl sulfoxide; at 120℃; for 12h;Inert atmosphere; General procedure: Under argon protection conditions,The CuI (9.55 mg, 0.05 mmol) and Cs2CO3 (652 mg, 2.0 mmol)Placed in a dry 25 mL two-necked flask, 5 mL of dry DMSO was added,Compound II-1 (170 mg, 1.0 mmol) was added in turnCompound III-1 (200 mg, 2.0 mmol) was added with stirring,The reaction was carried out at 90 C for about 12 hours (the time required to stop the reaction by TLC), cooled to room temperature, extracted three times with saturated brine and ethyl acetate, the organic phases were combined and the ethyl acetate was distilled off under reduced pressure.The residue was chromatographed on silica gel column chromatography (n-hexane: ethyl acetate = 25: 1 (v / v)) to give a white solid (compound I-1), m.p. 94.6-95.3 C, yield 88%
  • 2
  • [ 615-06-5 ]
  • [ 1608-24-8 ]
  • methyl 5-(4-methoxyphenyl)-[2,2'-bifuran]-3-carboxylate [ No CAS ]
 

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