Home Cart Sign in  
Chemical Structure| 1610520-29-0 Chemical Structure| 1610520-29-0

Structure of 1610520-29-0

Chemical Structure| 1610520-29-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1610520-29-0 ]

CAS No. :1610520-29-0
Formula : C9H6BrNO2S
M.W : 272.12
SMILES Code : O=CC(S1)=CC2=C1C(Br)=CN(C)C2=O

Safety of [ 1610520-29-0 ]

Application In Synthesis of [ 1610520-29-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1610520-29-0 ]

[ 1610520-29-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 496807-97-7 ]
  • [ 1610520-29-0 ]
  • [ 1610521-08-8 ]
YieldReaction ConditionsOperation in experiment
63.8% 3,3-Difluoropiperidine hydrochloride (319 mg, 2.02 mmol) was added to a stirred solution of 7- bromo-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridine-2-carbaldehyde (Intermediate 3) (500 mg, 1.84 mmol) in MeOH (9 mL) and glacial acetic acid (1 mL). The mixture was stirred at room temperature for 15 minutes then 2-picolineborane complex (216 mg, 2.02 mmol) was added. The reaction mixture was stirred at room temperature for 2 hours. The solvent was evaporated. Saturated sodium bicarbonate solution (15 mL) was added. The mixture was extracted with DCM (3x15 mL). The combined extracts were dried and evaporated. The residue was purified by column chromatography on silica gel (2-4% MeOH/DCM) to give the title compound (442 mg, 1 .172 mmol, 63.8 % yield) as a yellow solid. LCMS (2 min, Formic Acid): Rt = 0.85 min, MH+ = 377/379 Intermediate 96: 7-bromo-2-((3-fluoropiperidin-1 -yl)methyl)-5-methylthienor3,2-c1pyridin- 4(5H)-one The title compound was prepared using a method similar to that described for Intermediate 95. Yellow solid (346 mg, 0.963 mmol, 52.4 % yield). LCMS (2 min, Formic Acid): Rt = 0.49 min, MH+ = 359/361.
 

Historical Records