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Chemical Structure| 1613643-02-9 Chemical Structure| 1613643-02-9

Structure of 1613643-02-9

Chemical Structure| 1613643-02-9

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Product Details of [ 1613643-02-9 ]

CAS No. :1613643-02-9
Formula : C17H30BN3O4
M.W : 351.25
SMILES Code : O=C(OC(C)(C)C)NCCCN1N=CC(B2OC(C)(C)C(C)(C)O2)=C1
MDL No. :MFCD28717088

Safety of [ 1613643-02-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1613643-02-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1613643-02-9 ]

[ 1613643-02-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10016-52-1 ]
  • [ 1613643-02-9 ]
  • [ 1613643-03-0 ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In 1,4-dioxane; water; at 95 - 104℃; for 1.4h;Microwave irradiation; Inert atmosphere; Intermediate 1(0.7 mmol, 0.246 g) and <strong>[10016-52-1]2,8-dibromodibenzo[b,d]furan</strong> (0.3 mmol, 0.10 g) were added into a microwave tube under Argon. Dioxane (2 mL) and aqueous K2C03 (2 mmol, 1 mL, 2 M) were added. Then Pd(PPh3)4 (0.07 mmol, 0.082 g) was added. The mixture was under microwave irradiation (95°C, 1 hour then 104°C 24 minutes) with stirring. Thereaction was cooled down to room temperature and extracted with EtOAc and brine. The organic layer was dried over Na504 and evaporated under vacuum. The residue was purified with silica column (eluent: EtOAc/hexanes = 0/100 to 50/100, v/v). The obtained white solid was stirred in 1 mL dichloromethane and 0.5 mL at room temperature for 4 hours. Then the mixture was evaporated and the residue was washed with ether. A white solid (0.022 g) was obtained as the product after freeze-dry. LC-MS and ?HNMR agreed.
 

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