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Chemical Structure| 1616360-23-6 Chemical Structure| 1616360-23-6

Structure of 1616360-23-6

Chemical Structure| 1616360-23-6

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Product Details of [ 1616360-23-6 ]

CAS No. :1616360-23-6
Formula : C8H9N5
M.W : 175.19
SMILES Code : NC1=CC(C2=NC=NC=C2)=NN1C

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Application In Synthesis of [ 1616360-23-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1616360-23-6 ]

[ 1616360-23-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 24078-12-4 ]
  • [ 1616360-23-6 ]
  • [ 1616360-22-5 ]
YieldReaction ConditionsOperation in experiment
51% With toluene-4-sulfonic acid; In acetonitrile; at 20 - 50℃; for 21h; To the suspension of 1-methyl-3-(pyrimidin-4-yl)-1H-pyrazol-5-amine (0.42 g, 2.4 mmol, prepared using A with methylpyrimidine-4-carboxylate (Ark Pharm) with NaH followed by B with methyl hydrazine) and <strong>[24078-12-4]4-bromo-2-methylbenzaldehyde</strong> (0.48 g, 2.40 mmol, Ark Pharm) in acetonitrile (15 mL) was added p-TSA (0.09 g, 0.5 mmol) and heated to about 50 C. for about 5 h. The reaction mixture was cooled to ambient temperature and continued to stir for about 16 h. The precipitate was collected by filtration and dried under reduced pressure to afford 4-(4-bromo-2-methylbenzylidene)-1-methyl-3-(pyrimidin-4-yl)-1H-pyrazol-5(4H)-imine (0.43 g, 51%) as a light brown solid. LC-MS MS (Table 1, Method g) Rt=2.48 min, m/z 356, 358 (M+H)+.
  • 2
  • [ 24078-12-4 ]
  • [ 1616360-23-6 ]
  • [ 1616360-21-4 ]
 

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