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Chemical Structure| 1622008-73-4 Chemical Structure| 1622008-73-4

Structure of 1622008-73-4

Chemical Structure| 1622008-73-4

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Product Details of [ 1622008-73-4 ]

CAS No. :1622008-73-4
Formula : C46H40N2O6S
M.W : 748.88
SMILES Code : COC1=CC=C(N(C2=CC=C(OC)C=C2)C3=CC=C(C4=C5OCCOC5=C(C6=CC=C(C=C6)N(C7=CC=C(OC)C=C7)C8=CC=C(OC)C=C8)S4)C=C3)C=C1
MDL No. :MFCD28369275
InChI Key :JOJPNOVYPGLCMM-UHFFFAOYSA-N
Pubchem ID :102130343

Safety of [ 1622008-73-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 1622008-73-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1622008-73-4 ]

[ 1622008-73-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 201802-29-1 ]
  • [ 174508-31-7 ]
  • [ 1622008-73-4 ]
YieldReaction ConditionsOperation in experiment
1.3 g With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; for 6h;Inert atmosphere; Reflux; Darkness; Compound 1 (0.3 g, 2.11 mmol) and N-bromosuccinimide (NBS)?(0.75 g, 4.22 mmol) were dissolved in 20 mL fleshly distilled THE and stirred at r.t. for 2 hr under N2. The reaction solution was transferred by syringe to a N2 protected 50 mL flask containing K2C03 (2 M, 5 ml), Pd(0)(PPh3)4 (0.129,0.1 mmol) and compound 4(1.47 g, 4.22 mmol). The reaction mixture was then stirred at reflux in the dark for 6 hr. The reaction mixture was cooled down to r.t. and poured into water, extracted with dichioromethane (DCM) and washed with water. The DCM layer was dried over MgSO4, concentrated and the residue mixture was purified by column chromatography on silica gel elutirig with DCM to obtain the product as a yellow solid (1.3 g, 82%). 1H NMR (CD2CI2) 6: 7.55 (br, 4H), 7.07 (d, J = 8.4 Hz, 8H), 6.90 (d, J = 7.6 Hz, 4H), 6.86 (d, J = 8.8 Hz, 12H), 4.34 (s, 4H), 3.81 (s, 12H). 13C NMR (CD2CI2) 6: 156.5, 147.7, 141.1, 138.3, 127.0, 125.8, 120.9, 115.1, 65.1, 55.9. HRMS (MALDI-TOF): calcd for C46H40N206S, 748.2607; found, 748.2656. Anal. calcd. for C46H40N206S: C, 73.78; H, 5.38; N, 3.74; S, 4.28 %. Found: C, 74.01; H, 5.29; N, 3.70; S, 4.21 %.
 

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