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Chemical Structure| 163210-22-8 Chemical Structure| 163210-22-8

Structure of 163210-22-8

Chemical Structure| 163210-22-8

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Product Details of [ 163210-22-8 ]

CAS No. :163210-22-8
Formula : C13H25NO3
M.W : 243.34
SMILES Code : O=C(N1CC(CCCO)CCC1)OC(C)(C)C
MDL No. :MFCD23701755

Safety of [ 163210-22-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 163210-22-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 163210-22-8 ]

[ 163210-22-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 352004-58-1 ]
  • [ 163210-22-8 ]
YieldReaction ConditionsOperation in experiment
97% With borane-THF; In tetrahydrofuran; at 20.0℃; for 16.0h;Inert atmosphere; To a solution of commercially available <strong>[352004-58-1]3-[1-(tert-butoxycarbonyl)-3-piperidinyl]propionic acid</strong> (2.57 g, 10.0 mmol) in 100 mL of anhydrous THF was added slowly a solution of BH3.THF complex in THF (1.0 M, 20 mL, 2.0 equiv) at room temperature under N2. The solution was stirred for 16 h at room temperature. Water was added carefully (hydrogen evolution.), and the resulting solution was concentrated under reduced pressure. The residue was diluted with water and extracted with EtOAc. The combined organic layers were washed with brine and dried over Na2SO4. The solvent was removed under reduced pressure to give the alcohol (2.35 g, 97%) as a colorless oil. LC-MS (ESI) m/z 244 (M+H+).
 

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