Alternatived Products of [ 1643-78-3 ]
Product Details of [ 1643-78-3 ]
CAS No. : | 1643-78-3 |
MDL No. : | MFCD23135741 |
Formula : |
C7H6FNO3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
171.13
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 1643-78-3 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 1643-78-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1643-78-3 ]
- 1
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[ 1737-21-9 ]
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[ 1643-78-3 ]
Yield | Reaction Conditions | Operation in experiment |
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With hydroxylamine hydrochloride; sodium ethanolate In ethanol |
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With hydroxylamine hydrochloride; sodium hydroxide In 1,4-dioxane; water at 20℃; for 12h; |
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Reference:
[1]Ostaszyuski,A. et al.
[Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1960, vol. 8, p. 591 - 597]
[2]He, Guangchao; Peng, Kewen; Song, Qiao; Wang, Junwei; Xu, Anhua; Xu, Yungen; Zhu, Qihua
[Bioorganic and medicinal chemistry letters, 2020, vol. 30, # 13]
- 2
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[ 1800-54-0 ]
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[ 22717-55-1 ]
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[ 61799-78-8 ]
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[ 1643-78-3 ]
Yield | Reaction Conditions | Operation in experiment |
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With hydroxylamine hydrochloride; sodium methylate; In methanol; |
EXAMPLE 2 Preparation of 4-Chlorosalicylohydroxamic acid STR50 Hydroxylamine hydrochloride (20.65 g, 0.297 mol) is added to a mixture of sodium methoxide (53 g, 0.99 mol) in methanol while maintaining the temperature below 10 C. A mixture of <strong>[22717-55-1]methyl 4-chlorosalicylate</strong> (46.2 g, 0.248 mol) in methanol is then added to the reaction mixture and the resultant mixture is stirred at room temperature for 10 days, acidified with concentrated hydrochloric acid (pH3) and filtered to give the title product as an off-white solid which is identified by NMR spectral analyses. Using essentially the same procedure, but substituting phenyl 4-fluorosalicylate for <strong>[22717-55-1]methyl 4-chlorosalicylate</strong>, 4-fluorosalicylohydroxamic acid is obtained as a peach-white solid, mp 184 C. (dec.). |
- 3
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[ 392-04-1 ]
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[ 1643-78-3 ]