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Chemical Structure| 165283-98-7 Chemical Structure| 165283-98-7

Structure of 165283-98-7

Chemical Structure| 165283-98-7

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Product Details of [ 165283-98-7 ]

CAS No. :165283-98-7
Formula : C10H8N2OS
M.W : 204.25
SMILES Code : N#CC1=CC2=C(NC1=S)CCCC2=O
MDL No. :MFCD01541462

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Application In Synthesis of [ 165283-98-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 165283-98-7 ]

[ 165283-98-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 25625-57-4 ]
  • [ 165283-98-7 ]
  • 3-amino-5-hydroxy-N-(3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide [ No CAS ]
  • 2
  • [ 25625-57-4 ]
  • [ 165283-98-7 ]
  • [ 663218-08-4 ]
YieldReaction ConditionsOperation in experiment
88% With sodium carbonate; In ethanol; for 18h;Inert atmosphere; Reflux; General procedure: A mixture of 2-bromoacetamides 21a-i (0.49 mmol), 5-oxo-2-thioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile 18(0.49 mmol) and anhydrous sodium carbonate (0.52 mmol) in absolute ethanol (2 mL) was stirred at reflux for 18 h. The mixture was cooled to room temperature, and the solvent was removed in vacuo.The crude product was washed using small amounts of water and the remaining solid, filtered and recrystallized from methanol to give the 5-oxo-tetrahydrothieno[2,3-b]quinolines 17a-i.
 

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