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Chemical Structure| 16536-93-9 Chemical Structure| 16536-93-9

Structure of 16536-93-9

Chemical Structure| 16536-93-9

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Product Details of [ 16536-93-9 ]

CAS No. :16536-93-9
Formula : C4H9NS
M.W : 103.19
SMILES Code : CCCC(N)=S
MDL No. :MFCD09802520

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Application In Synthesis of [ 16536-93-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 16536-93-9 ]

[ 16536-93-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 16536-93-9 ]
  • [ 33142-21-1 ]
  • [ 50680-74-5 ]
  • 2
  • [ 16536-93-9 ]
  • [ 33142-21-1 ]
  • magnesium carbonate [ No CAS ]
  • [ 50680-74-5 ]
YieldReaction ConditionsOperation in experiment
In 1,4-dioxane; ethyl ether-water; STEP B: Ethyl 2-n-propylthiazol-5-carboxylate A mixture of 38 g of thiobutyramide, 54.2 g of <strong>[33142-21-1]ethyl 2-formyl-2-chloro-acetate</strong>, 185 ml of dioxane and 22 g of magnesium carbonate was heated for 4 hours at 60C and the precipitate formed was removed by filtration. The dioxane was distilled from the filtrate and the residue was taken up in 665 ml of a 1-1 ethyl ether-water mixture. The ether phase was recovered by decantation and was washed with aqueous 10% hydrochloric acid solution and then with water until the wash waters were neutral, dried over magnesium sulfate and distilled to dryness. The residue was distilled to obtain 57 g of ethyl 2-n-propylthiazol-5-carboxylate boiling at 95-106C under 0.5 mm Hg.
 

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