Alternatived Products of [ 166338-06-3 ]
Product Details of [ 166338-06-3 ]
CAS No. : | 166338-06-3 |
MDL No. : | MFCD07957223 |
Formula : |
C12H10BrNO2S
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
312.18
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 166338-06-3 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 166338-06-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 166338-06-3 ]
- 1
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[ 761446-45-1 ]
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[ 166338-06-3 ]
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[ 1197896-82-4 ]
- 2
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[ 22033-09-6 ]
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[ 62-53-3 ]
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[ 166338-06-3 ]
Yield | Reaction Conditions | Operation in experiment |
96% |
With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride at 50℃; for 2h; |
1.1; 2.1; 3.1; 4.1; 5.1 (1) Synthesis of 3-bromo-N-phenylbenzenesulfonamide
Take a 100ml single-necked bottle, add 4.74g (0.02mol) of 3-bromobenzenesulfonic acid, and add 100mL of pyridine,Stir to dissolve, then add 2.23g (0.024mol) of aniline,Then slowly add the condensing agent EDC-HCl 5.73g (0.04mol) to the reaction solution in batches,Then heated to 50 for 2h, spin-distilled to remove pyridine, pour residual water into a separatory funnel,Add appropriate amount of ethyl acetate to extract 3 times,The ethyl acetate layer was washed once with dilute hydrochloric acid water,The organic layers were combined, the organic layer was dried over anhydrous sodium sulfate, and the solvent was removed under reduced pressure to obtain 5.99 g of a white solid in 96% yield. |