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Chemical Structure| 1679-36-3 Chemical Structure| 1679-36-3

Structure of 1679-36-3

Chemical Structure| 1679-36-3

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Product Details of [ 1679-36-3 ]

CAS No. :1679-36-3
Formula : C6H8O
M.W : 96.13
SMILES Code : CC(C#CCC)=O
MDL No. :MFCD00041627

Safety of [ 1679-36-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H301-H315-H319
Precautionary Statements:P210-P233-P241-P264-P270-P280-P362-P405-P501
Class:3(6.1)
UN#:1992
Packing Group:

Application In Synthesis of [ 1679-36-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1679-36-3 ]

[ 1679-36-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1679-36-3 ]
  • [ 14150-94-8 ]
  • 2-butyn-1-yl-5-nitropyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
80% With ammonium acetate; In ethanol; at 80℃; for 3h;Microwave irradiation; General procedure: To a solution of the dinitropyridone 1 (50 mg, 0.25 mmol) in ethanol (10 mL), 4-phenyl-3-buten-2-one (4a) (36.5 mg, 0.25 mmol) and NH4OAc (578 mg, 7.5 mmol) were added, and the resultant mixture was heated at 65 C for 24 h. After removal of the solvent, the residue was washed with benzene (3 × 10 mL) to remove unreacted ketone 4a and treated with column chromatography on silica gel (eluent: hexane/ethyl acetate =95/5) to afford 5-nitro-2-(2-phenylethenyl)pyridine (5a) (41 mg, 0.18 mmol, 72%) as a yellow powder. The reactions of the dinitropyridone 1 with other ketones 4b-f or 10a-c were performed in a similar way.
  • 2
  • [ 1679-36-3 ]
  • [ 57508-48-2 ]
  • ethyl 2-amino-4-ethyl-6-methylnicotinate [ No CAS ]
YieldReaction ConditionsOperation in experiment
54% With sodium carbonate; In ethanol; at 150℃; for 1.5h;Microwave irradiation; General procedure: an ethanolic solution of <strong>[57508-48-2]ethyl 3-amino-3-iminopropionate hydrochloride</strong> (6*HCl; 1equiv) was pretreated with Na2CO3 (1 equiv) for 10 min. After filtering, the ethynyl ketone (1.05 equiv) was added and the mixture in EtOH (3.5 mL) was irradiated at 150 C for 1.5 h (holdtime) in a pressure-rated glass tube (10 mL) using a CEM Discover microwave synthesizer by moderation of the initial magnetron power (200 W). After cooling in a flow of compressed air,the solution was immobilized on a Biotage ISOLUTE SCX-2column and eluted with EtOH-NH4OH (aq; 35%; 5:1) or ethanolic NH3 (2 M) to give the title compound.
 

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