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Chemical Structure| 17100-68-4 Chemical Structure| 17100-68-4

Structure of 17100-68-4

Chemical Structure| 17100-68-4

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Product Details of [ 17100-68-4 ]

CAS No. :17100-68-4
Formula : C12H15BrO2
M.W : 271.15
SMILES Code : BrC1=CC=C(C=C1)COC2CCCCO2

Safety of [ 17100-68-4 ]

Application In Synthesis of [ 17100-68-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17100-68-4 ]

[ 17100-68-4 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 17100-68-4 ]
  • [ 3282-99-3 ]
  • [ 1352733-65-3 ]
YieldReaction ConditionsOperation in experiment
With sodium t-butanolate;tri-tert-butyl phosphine; palladium diacetate; In o-xylene; at 20 - 80℃; for 2h;Inert atmosphere; Reflux; Synthesis Example 9 (Example 5·' synthesis of atetrahydropyranyl compound No. 5 shown as an example)]In a four-necked flask, 9.323 g ofl, l-bis(4-aminophenyl)cyclohexene, 45.55 g of the compound obtained in Synthesis Example 5, 0.785 g of palladium acetate, 32.289 g of tert-butoxysodium and 300 mL of o-xylene were placed.In an argon gas atmosphere, the above ingredients were stirred at room temperature.Dropwise addition of 2.43 g of tri-tert-butylphosphine was carried out.Stirring was continued for 1 hour at 80C and 2 hours in a state of reflux.The ingredients were diluted with toluene, which was followed by addition of magnesium sulfate, activated clay and silica gel, and then stirring was carried out.The ingredients were filtered, washed and concentrated to obtain yellow oily matter.A column cleanup with silica gel (toluene / ethyl acetate = 5/1) was performed so as to effect isolation, and an intended product was thus obtained (yield-' 11.42 g, yellow amorphous product).A diagram showing an infrared absorption spectrum of the compound obtained in Synthesis Example 9 (KBr tablet method) is in FIG. 9.
 

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