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Chemical Structure| 171565-43-8 Chemical Structure| 171565-43-8

Structure of 171565-43-8

Chemical Structure| 171565-43-8

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Product Details of [ 171565-43-8 ]

CAS No. :171565-43-8
Formula : C13H8N4
M.W : 220.23
SMILES Code : C12=NC=CC=C1C3=C(NC=N3)C4=CC=CN=C24

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Application In Synthesis of [ 171565-43-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 171565-43-8 ]

[ 171565-43-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4761-00-6 ]
  • [ 171565-43-8 ]
  • C23H20N4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% General procedure: IP (2.00 g, 9.10 mmol) and KOH (0.61 g, 11.0 mmol) were dissolved in acetone. The mixture was stirred and heated under reflux for 1 h. Then, different aryl or alkyl bromides (9.10 mmol) were added and kept on refluxing for 48 h. The volatiles were removed under vacuum and then the residue was dissolved with DCM (5.00 mL) and filtered with cannula. Diethylether was added to the solution. Obtained light brown precipitate was filtered and dried under vacuum. 4.3.5 Compound L4a. Yield: 2.60 g, 90%. 1H NMR (400 MHz, CDCl3): delta 9.19 (dd, J=14.3, 3.0 Hz, 2H, phen-H), 8.98 (d, J=8 Hz, 1H, phen-H), 8.90 (d, J=8.2 Hz, 1H, phen-H), 7.73 (m, 2H, phen-H), 7.38 (s, 1H, C2-H), 7.04 (s, 2H, Ar-H), 5.74 (s, 2H, Ar-CH2), 2.38 (s, 3H, Ar-CH3), 2.29 (s, 6H, Ar-CH3). 13C NMR (100 MHz, CDCl3): delta 149.0, 148.0, 145.0, 144.2, 140.7, 139.6, 138.0, 137.7, 130.36, 130.0, 128.7, 126.6, 124.8, 124.5, 123.6, 122.7, 120.5, 47.3, 21.2, 19.5. IR, numax (CH2Cl2): 3376, 2969, 2849, 1737, 1562, 1518, 1349, 1217, 1006, 804, 742. Anal. Calcd for C23H20N4 (M=352.43): C, 78.38; H, 5.72; N, 15.90. Found C, 78.26; H, 5.64; N, 15.72%.
 

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