Home Cart Sign in  
Chemical Structure| 173159-42-7 Chemical Structure| 173159-42-7

Structure of 173159-42-7

Chemical Structure| 173159-42-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 173159-42-7 ]

CAS No. :173159-42-7
Formula : C8H7ClN2
M.W : 166.61
SMILES Code : CC1=CN2C=CC=C(Cl)C2=N1
MDL No. :MFCD09959726
InChI Key :DLIKCSGMQBOHGQ-UHFFFAOYSA-N
Pubchem ID :55267532

Safety of [ 173159-42-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 173159-42-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 173159-42-7 ]

[ 173159-42-7 ] Synthesis Path-Downstream   1~1

YieldReaction ConditionsOperation in experiment
54% In ethanol; for 3.0h;Reflux; General procedure: 3-Chloropyridin-2-amine (15 g, 117 mmol) was dissolved in ethanol (117 mL), 2-bromo-1-cyclopropylethanone (22.8 g, 140 mmol) was added, and the mixture was stirred with heating under reflux for 3 hr. The mixture was concentrated under reduced pressure, ethyl acetate (60 mL) was added to the obtained residue, and the resulting precipitate was collected by suction filtration to give white crystals (27.2 g). The obtained crystals were dissolved in water (300 mL), saturated aqueous sodium hydrogen carbonate solution (100 mL) was added, and the precipitated crystals were collected by suction filtration to give 8-chloro-2-cyclopropylimidazo[1,2-a]pyridine (16 g, 71.4%). ESIMS m/z: 193 (M + H)+; 1H NMR (270 MHz, CDCl3, delta): 0.84-0.93 (m, 2H), 0.93-1.06 (m, 2H), 2.01-2.17 (m, 1H), 6.64 (t, J = 7.2 Hz, 1H), 7.17 (dd, J = 7.2, 1.4 Hz, 1H), 7.33 (s, 1H), 7.94 (dd, J = 7.2, 1.4 Hz, 1H).
 

Historical Records

Technical Information

Categories