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Chemical Structure| 17510-79-1 Chemical Structure| 17510-79-1

Structure of 17510-79-1

Chemical Structure| 17510-79-1

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Product Details of [ 17510-79-1 ]

CAS No. :17510-79-1
Formula : C4H6N2O2S2
M.W : 178.23
SMILES Code : O=S(=O)(N)C1SC(N)=CC=1
MDL No. :MFCD09951500

Safety of [ 17510-79-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 17510-79-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17510-79-1 ]

[ 17510-79-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17510-79-1 ]
  • [ 444731-75-3 ]
  • 5-[[4-(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-ylamino] thiophene-2-sulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
37% With hydrogenchloride; In isopropyl alcohol; at 90℃; for 4h;Inert atmosphere; Specific reaction formula is as follows:The 5-amino-thiophene-2-sulfonyl-ammonia (100 mg, 0 . 56mmol) and 2, 3-dimethyl-N-(2-chloro-pyrimidin-4-yl)-N-methyl -2H-indazol-6-amine (177 mg, 0 . 62mmol) is added to the isopropanol (4 ml) in, evacuation, using N2 gas replacement, then adding concentrated hydrochloric acid (0.3 ml), heating to 90 C after-reaction 4h, TLC tracking reaction, after the end of the reaction is complete to, neutralized with triethylamine, adjusting PH=8 rear, reducing pressure and evaporating the solvent, the residue by silica gel column chromatography separation (CH2Cl2: CH3OH=20:1), get compound 190 mg, grey and white solid, yield is 37%,
 

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