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Chemical Structure| 17510-80-4 Chemical Structure| 17510-80-4

Structure of 17510-80-4

Chemical Structure| 17510-80-4

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Product Details of [ 17510-80-4 ]

CAS No. :17510-80-4
Formula : C4H6N2O2S2
M.W : 178.22
SMILES Code : O=S(C1=CC(N)=CS1)(N)=O
MDL No. :MFCD14620229

Safety of [ 17510-80-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 17510-80-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17510-80-4 ]

[ 17510-80-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17510-80-4 ]
  • [ 444731-75-3 ]
  • [[4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl]amino]thiophene-2-sulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
35% With hydrogenchloride; In isopropyl alcohol; at 90℃; for 5h;Inert atmosphere; The 4-amino-thiophene-2-sulfonyl-ammonia (112 mg, 0 . 63mmol) and 2, 3-dimethyl-N-(2-chloro-pyrimidin-4-yl)-N-methyl -2H-indazol-6-amine (200 mg, 0 . 70mmol) is added to the isopropanol (4 ml) in, evacuation, replacement N2 gas, then adding concentrated hydrochloric acid (0.3 ml), heating to 90 C after-reaction 5h, TLC tracking reaction, after the end of the reaction is complete to, neutralized with triethylamine, adjusting PH=8 rear, reducing pressure and evaporating the solvent, the residue by silica gel column chromatography separation (CH2Cl2: CH3OH=20:1), get compound 295 mg, pale yellow solid, yield is 35%.
 

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