Alternatived Products of [ 175676-42-3 ]
Product Details of [ 175676-42-3 ]
CAS No. : | 175676-42-3 |
MDL No. : | MFCD31695793 |
Formula : |
C8H7F3O3S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | NHBKFPDJMAEDOS-UHFFFAOYSA-N |
M.W : |
240.20
|
Pubchem ID : | 13494930 |
Synonyms : |
|
Safety of [ 175676-42-3 ]
Application In Synthesis of [ 175676-42-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 175676-42-3 ]
- 1
-
[ 175676-42-3 ]

-
[ 1454-85-9 ]

-
1-(trifluoromethoxy)heptadecane
[ No CAS ]
- 2
-
[ 175676-42-3 ]

-
[ 262373-15-9 ]

-
2-iodo-5-methyl-1-(trifluoromethoxy)benzene
[ No CAS ]

-
2-iodo-4-methyl-1-(trifluoromethoxy)benzene
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With potassium fluoride; 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane; cis-dicyclohexano-18-C-6; carbonic acid dimethyl ester; at 60℃; for 12h; |
General procedure: To a 15 mL of pressure-proof pipe equipped with a stir bar was added 1 (0.50 mmol, 1.00 equiv), cis-DCy-18-C-6 (372.49 mg, 1.00 mmol, 2.0 equiv), C4F9I (1037.79 mg, 3.00 mmol, 6.00 equiv) and DMC (3.0 mL) in the glove box. 2a (240.20 mg, 1.00 mmol, 2.0 equiv) and KF (116.20 mg, 2.00 mmol, 4.00 equiv) were added with stirring at room temperature. The reaction was stirred at 60 C for 12 h and cooled to room temperature. The solvent was evaporated under vacuum and the crude product was purified by flash column chromatography to give products 3. Yields were listed in Table 5. The ratio of regioisomer ab/ba was determined by 19F NMR spectroscopy. |
- 3
-
[ 175676-42-3 ]

-
[ 88284-48-4 ]

-
[ 175278-00-9 ]
Yield | Reaction Conditions | Operation in experiment |
64% |
With potassium fluoride; 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane; cis-dicyclohexano-18-C-6; carbonic acid dimethyl ester; at 60℃; for 12h; |
General procedure: To a 15 mL of pressure-proof pipe equipped with a stir bar was added 1 (0.50 mmol, 1.00 equiv), cis-DCy-18-C-6 (372.49 mg, 1.00 mmol, 2.0 equiv), C4F9I (1037.79 mg, 3.00 mmol, 6.00 equiv) and DMC (3.0 mL) in the glove box. 2a (240.20 mg, 1.00 mmol, 2.0 equiv) and KF (116.20 mg, 2.00 mmol, 4.00 equiv) were added with stirring at room temperature. The reaction was stirred at 60 C for 12 h and cooled to room temperature. The solvent was evaporated under vacuum and the crude product was purified by flash column chromatography to give products 3. Yields were listed in Table 5. The ratio of regioisomer ab/ba was determined by 19F NMR spectroscopy. |
- 4
-
[ 175676-42-3 ]

-
[ 88284-48-4 ]

-
[ 456-55-3 ]

-
[ 175278-00-9 ]
- 5
-
[ 175676-42-3 ]

-
[ 57280-22-5 ]

-
C8H13F3O4
[ No CAS ]
- 6
-
[ 175676-42-3 ]

-
[ 31865-25-5 ]

-
C13H14F3NO4
[ No CAS ]