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Chemical Structure| 17832-99-4 Chemical Structure| 17832-99-4

Structure of 17832-99-4

Chemical Structure| 17832-99-4

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Product Details of [ 17832-99-4 ]

CAS No. :17832-99-4
Formula : C8H7NO3
M.W : 165.15
SMILES Code : O=C1OC2=CC=CC=C2N1CO

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Application In Synthesis of [ 17832-99-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17832-99-4 ]

[ 17832-99-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17832-99-4 ]
  • [ 5466-31-9 ]
  • (2-oxobenzo[d]oxazol-3(2H)-yl)methyl-2-(4-chlorophenyl)quinoline-4-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 5℃; for 2h; General procedure: To an ice-cold solution of the 2-aryl quinoline-4-carboxylic acid derivatives (3 mmol) in 10 mL DMF,3-(hydroxymethyl)benzo[d]oxazol-2(3H)-one (3mmol),dimethyl-aminopyridine (DMAP, 20 mg), and dicyclohexylcarbodiimde(DCC, 3.5 mmol) were added.The reaction mixture was stirred at 5C for 2 h andkept overnight at room temperature. The precipitateformed was separated by filtration. Ethyl acetate wasadded to the filtrate and was washed with cooled0.05 N HCl followed by saturated solution of NaHCO3and finally with brine. The organic layer wasdried over anhydrous Na2SO4 and evaporated underreduced pressure. The residue obtained was crystallisedtwice with ethanol to afford pure product.
 

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