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Chemical Structure| 18065-03-7 Chemical Structure| 18065-03-7

Structure of 18065-03-7

Chemical Structure| 18065-03-7

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Product Details of [ 18065-03-7 ]

CAS No. :18065-03-7
Formula : C14H11NO4
M.W : 257.24
SMILES Code : O=C(C1=CC=CC=C1)COC2=CC=C([N+]([O-])=O)C=C2

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Application In Synthesis of [ 18065-03-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18065-03-7 ]

[ 18065-03-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 18065-03-7 ]
  • [ 1597-32-6 ]
  • 5-fluoro-3-(4-nitrophenoxy)-2-phenylimidazo[1,2-a]pyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
91% With iodine; In 1,2-dichloro-ethane; at 100℃; for 0.5h; General procedure: A dried glass reaction tube equipped with a magnetic stir bar was charged with 1 (106 mg, 0.5 mmol), 2 or 4 (141.2 mg, or 207 mg,1.5 mmol), I2 (254 mg, 1 mmol) in DCE (10 mL); stirred at 100 C for30 min. The solvent was evaporated under vacuum, and washed with saturated sodium thiosulfate solution, water, brine. The organic layer was dried over anhydrous Na2SO4, filtered, and concentrated to give the crude product, which was purified through flash column chromatography (ethyl acetate in petroleum ether) to give the desired product.
 

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