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Chemical Structure| 182344-15-6 Chemical Structure| 182344-15-6

Structure of 182344-15-6

Chemical Structure| 182344-15-6

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Product Details of [ 182344-15-6 ]

CAS No. :182344-15-6
Formula : C14H23BO3
M.W : 250.14
SMILES Code : OC1=C(C(C)(C)C)C=C(B(O)O)C=C1C(C)(C)C
MDL No. :MFCD28147739
InChI Key :WFMIGOJEPFFIHE-UHFFFAOYSA-N
Pubchem ID :22125386

Safety of [ 182344-15-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 182344-15-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 182344-15-6 ]

[ 182344-15-6 ] Synthesis Path-Downstream   1~4

  • 2
  • [ 1139-52-2 ]
  • [ 81050-39-7 ]
  • [ 182344-15-6 ]
  • 3
  • [ 5419-55-6 ]
  • [ 1139-52-2 ]
  • [ 182344-15-6 ]
YieldReaction ConditionsOperation in experiment
23% Preparative Example P8 (3,5-Di-fert-butyl-4-hvdroxyphenyl)boronic acid To a -78°C cooled solution of 4-bromo-2,6-di-fert-butylphenol (2.00 g, 7.0 mmol) in dry THF (30 mL) was added dropwise a 1.3M solution of ferf-BuLi in hexane (18 mL, 20 mmol). The mixture was stirred for 1 h at rt and cooled to -78°C prior to the addition of tri-/'sopropyl borate (5 mL, 21 mmol), stirred overnight at rt, diluted with sat. NH4CI solution, stirred at rt for 2 h and extracted with EA twice. The combined organic layers were washed with brine, dried over MgS04, filtered, evaporated and purified by recrystallization (30percent EA in hexane) to give compound P8 (400 mg, 23percent) as a white solid.
  • 4
  • [ 121-43-7 ]
  • [ 1139-52-2 ]
  • [ 182344-15-6 ]
 

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[ 182344-15-6 ]

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